Mechanobiology of collective cell behaviours

B Ladoux, RM Mège - Nature reviews Molecular cell biology, 2017 - nature.com
The way in which cells coordinate their behaviours during various biological processes,
including morphogenesis, cancer progression and tissue remodelling, largely depends on …

Cancer cell motility: lessons from migration in confined spaces

CD Paul, P Mistriotis, K Konstantopoulos - Nature reviews cancer, 2017 - nature.com
Time-lapse, deep-tissue imaging made possible by advances in intravital microscopy has
demonstrated the importance of tumour cell migration through confining tracks in vivo. These …

Single and collective cell migration: the mechanics of adhesions

C De Pascalis… - Molecular biology of the …, 2017 - Am Soc Cell Biol
Chemical and physical properties of the environment control cell proliferation, differentiation,
or apoptosis in the long term. However, to be able to move and migrate through a complex …

An introduction to the wound healing assay using live-cell microscopy

JEN Jonkman, JA Cathcart, F Xu… - Cell adhesion & …, 2014 - Taylor & Francis
The wound healing assay is used in a range of disciplines to study the coordinated
movement of a cell population. In this technical review, we describe the workflow of the …

[HTML][HTML] Plasticity of cancer cell invasion: Patterns and mechanisms

J Wu, J Jiang, B Chen, K Wang, Y Tang, X Liang - Translational oncology, 2021 - Elsevier
Cancer cell migration and invasion are integral components of metastatic disease, which is
the major cause of death in cancer patients. Cancer cells can disseminate and migrate via …

Collective behaviors of active matter learning from natural taxes across scales

F Ji, Y Wu, M Pumera, L Zhang - Advanced Materials, 2023 - Wiley Online Library
Taxis orientation is common in microorganisms, and it provides feasible strategies to
operate active colloids as small‐scale robots. Collective taxes involve numerous units that …

Collective cell migration: guidance principles and hierarchies

A Haeger, K Wolf, MM Zegers, P Friedl - Trends in cell biology, 2015 - cell.com
Collective cell migration results from the establishment and maintenance of collective
polarization, mechanocoupling, and cytoskeletal kinetics. The guidance of collective cell …

Topological defects in epithelia govern cell death and extrusion

TB Saw, A Doostmohammadi, V Nier, L Kocgozlu… - Nature, 2017 - nature.com
Epithelial tissues (epithelia) remove excess cells through extrusion, preventing the
accumulation of unnecessary or pathological cells. The extrusion process can be triggered …

Forces driving epithelial wound healing

A Brugués, E Anon, V Conte, JH Veldhuis, M Gupta… - Nature physics, 2014 - nature.com
A fundamental feature of multicellular organisms is their ability to self-repair wounds through
the movement of epithelial cells into the damaged area. This collective cellular movement is …

The role of single-cell mechanical behaviour and polarity in driving collective cell migration

S Jain, VML Cachoux, GHNS Narayana, S de Beco… - Nature physics, 2020 - nature.com
The directed migration of cell collectives is essential in various physiological processes,
such as epiboly, intestinal epithelial turnover, and convergent extension during …