Hairy root cultures—a versatile tool with multiple applications

N Gutierrez-Valdes, ST Häkkinen… - Frontiers in plant …, 2020 - frontiersin.org
Hairy roots derived from the infection of a plant by Rhizobium rhizogenes (previously
referred to as Agrobacterium rhizogenes) bacteria, can be obtained from a wide variety of …

Polyamines and their possible mechanisms involved in plant physiological processes and elicitation of secondary metabolites

SH Mustafavi, H Naghdi Badi, A Sękara… - Acta Physiologiae …, 2018 - Springer
Polyamines are amine-containing, low molecular weight, and ubiquitous polycationic
molecules present in almost all cells and free-living microbes, which are formed by aliphatic …

Hairy root culture for mass-production of high-value secondary metabolites

S Srivastava, AK Srivastava - Critical reviews in biotechnology, 2007 - Taylor & Francis
Plant cell cultivations are being considered as an alternative to agricultural processes for
producing valuable phytochemicals. Since many of these products (secondary metabolites) …

Hairy root research: recent scenario and exciting prospects

S Guillon, J Tremouillaux-Guiller, PK Pati… - Current opinion in plant …, 2006 - Elsevier
High stability of the production of secondary metabolites is an interesting characteristic of
hairy root cultures. For 25 years, hairy roots have been investigated as a biological system …

Hairy root and its application in plant genetic engineering

ZB Hu, M Du - Journal of integrative plant biology, 2006 - Wiley Online Library
Agrobacterium rhizogenes Conn. causes hairy root disease in plants. Hairy root‐infected A.
rhizogenes is characterized by a high growth rate and genetic stability. Hairy root cultures …

Hairy root culture technology: applications, constraints and prospect

S Gantait, E Mukherjee - Applied Microbiology and Biotechnology, 2021 - Springer
Hairy root (HR) culture, a successful biotechnology combining in vitro tissue culture with
recombinant DNA machinery, is intended for the genetic improvement of plants. This …

Hairy root culture: a potent method for improved secondary metabolite production of Solanaceous plants

D Biswas, A Chakraborty, S Mukherjee… - Frontiers in Plant …, 2023 - frontiersin.org
Secondary metabolites synthesized by the Solanaceous plants are of major therapeutic and
pharmaceutical importance, many of which are commonly obtained from the roots of these …

Engineering secondary metabolite production in hairy roots

S Chandra, R Chandra - Phytochemistry reviews, 2011 - Springer
Plants are a rich source of valuable secondary metabolites. Plant cell culture technologies
developed in the past as possible tools for secondary metabolites production. In most cases …

Hairy CRISPR: genome editing in plants using hairy root transformation

AS Kiryushkin, EL Ilina, ED Guseva, K Pawlowski… - Plants, 2021 - mdpi.com
CRISPR/Cas-mediated genome editing is a powerful tool of plant functional genomics. Hairy
root transformation is a rapid and convenient approach for obtaining transgenic roots. When …

Harnessing the potential of hairy roots: dawn of a new era

S Guillon, J Trémouillaux-Guiller, PK Pati… - TRENDS in …, 2006 - cell.com
In the past two decades, hairy root research for the production of important secondary
metabolites has received a lot of attention. The addition of knowledge to overcome the …