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Noble metals in medicine: Latest advances
History shows that metal-based drugs and remedies have been known and used since very
ancient times. For example, silver was employed in the treatment of wounds and ulcers …
ancient times. For example, silver was employed in the treatment of wounds and ulcers …
Non-covalent binding studies of transition metal complexes with DNA: A review
Transition metal complexes are widely used therapeutic agents due to their small size,
various coordination numbers, geometries, physiologically relevant redox potentials, as well …
various coordination numbers, geometries, physiologically relevant redox potentials, as well …
DNA-binding of nickel (II), copper (II) and zinc (II) complexes: Structure–affinity relationships
Abstract Nickel (II), copper (II) and zinc (II) complexes with the same ligands normally display
analogous coordination geometry and binding mode toward DNA. However, although …
analogous coordination geometry and binding mode toward DNA. However, although …
The antibacterial activity of metal complexes containing 1, 10-phenanthroline: potential as alternative therapeutics in the era of antibiotic resistance
L Viganor, O Howe, P McCarron… - Current topics in …, 2017 - ingentaconnect.com
The “antibiotic era”, characterized by the overuse and misuse of antibiotics, over the last half-
century has culminated in the present critical “era of resistance”. The treatment of bacterial …
century has culminated in the present critical “era of resistance”. The treatment of bacterial …
Advances in alkynyl gold complexes for use as potential anticancer agents
Z Yang, G Jiang, Z Xu, S Zhao, W Liu - Coordination Chemistry Reviews, 2020 - Elsevier
Gold-based anticancer agents have gained the widespread attention of medicinal inorganic
chemists due to their unique chemical properties and strong antiproliferative potency …
chemists due to their unique chemical properties and strong antiproliferative potency …
Progress of Metal‐Based anticancer chemotherapeutic agents in last two decades and their comprehensive biological (DNA/RNA Binding, Cleavage and Cytotoxicity …
During last two decades, there has been an enormous growth in the discovery of innovative
active inorganic anticancer complexes (exerting remarkable cytotoxicity at sub micro‐molar …
active inorganic anticancer complexes (exerting remarkable cytotoxicity at sub micro‐molar …
Co (ii) and Zn (ii) pyrazolyl-benzimidazole complexes with remarkable antibacterial activity
Three mononuclear coordination complexes of 1-butyl-2-((5-methyl-1H-pyrazol-3-yl) methyl)-
1H-benzimidazole (L), namely [CoL] Cl2 (C1),[Co2L2] Cl2· H2O (C2) and [Zn2L2] Cl2 (C3) …
1H-benzimidazole (L), namely [CoL] Cl2 (C1),[Co2L2] Cl2· H2O (C2) and [Zn2L2] Cl2 (C3) …
[HTML][HTML] Anticancer activity of Metallodrugs and metallizing host defense peptides—current developments in Structure-Activity relationship
CMC Andrés, JM Pérez de la Lastra… - International Journal of …, 2024 - mdpi.com
This article provides an overview of the development, structure and activity of various metal
complexes with anti-cancer activity. Chemical researchers continue to work on the …
complexes with anti-cancer activity. Chemical researchers continue to work on the …
Synthesis, spectroscopic, thermal and molecular modeling studies of Zn2+, Cd2+ and UO22+ complexes of Schiff bases containing triazole moiety. Antimicrobial …
A novel series of Zn 2+, Cd 2+ and UO 2 2+ complexes of ligands namely 1-[(5-mercapto-1H-
1, 2, 4-triazole-3-ylimino) methyl] naphthalene-2-ol (HL 1) and [(1H-1, 2, 4-triazole-3-ylimino) …
1, 2, 4-triazole-3-ylimino) methyl] naphthalene-2-ol (HL 1) and [(1H-1, 2, 4-triazole-3-ylimino) …
Current and future potential of metallo drugs: Revisiting DNA-binding of metal containing molecules and their diverse mechanism of action
Cancer treatments regimes which include conventional chemotherapy have not proved so
successful in curing human malignancies. Failures to these treatment modalities include …
successful in curing human malignancies. Failures to these treatment modalities include …