Noble metals in medicine: Latest advances

S Medici, M Peana, VM Nurchi, JI Lachowicz… - Coordination Chemistry …, 2015 - Elsevier
History shows that metal-based drugs and remedies have been known and used since very
ancient times. For example, silver was employed in the treatment of wounds and ulcers …

Non-covalent binding studies of transition metal complexes with DNA: A review

N Kumar, R Kaushal, P Awasthi - Journal of Molecular Structure, 2023 - Elsevier
Transition metal complexes are widely used therapeutic agents due to their small size,
various coordination numbers, geometries, physiologically relevant redox potentials, as well …

DNA-binding of nickel (II), copper (II) and zinc (II) complexes: Structure–affinity relationships

G Barone, A Terenzi, A Lauria, AM Almerico… - Coordination Chemistry …, 2013 - Elsevier
Abstract Nickel (II), copper (II) and zinc (II) complexes with the same ligands normally display
analogous coordination geometry and binding mode toward DNA. However, although …

The antibacterial activity of metal complexes containing 1, 10-phenanthroline: potential as alternative therapeutics in the era of antibiotic resistance

L Viganor, O Howe, P McCarron… - Current topics in …, 2017 - ingentaconnect.com
The “antibiotic era”, characterized by the overuse and misuse of antibiotics, over the last half-
century has culminated in the present critical “era of resistance”. The treatment of bacterial …

Advances in alkynyl gold complexes for use as potential anticancer agents

Z Yang, G Jiang, Z Xu, S Zhao, W Liu - Coordination Chemistry Reviews, 2020 - Elsevier
Gold-based anticancer agents have gained the widespread attention of medicinal inorganic
chemists due to their unique chemical properties and strong antiproliferative potency …

Progress of Metal‐Based anticancer chemotherapeutic agents in last two decades and their comprehensive biological (DNA/RNA Binding, Cleavage and Cytotoxicity …

F Arjmand, H Yasir Khan, S Tabassum - The Chemical Record, 2023 - Wiley Online Library
During last two decades, there has been an enormous growth in the discovery of innovative
active inorganic anticancer complexes (exerting remarkable cytotoxicity at sub micro‐molar …

Co (ii) and Zn (ii) pyrazolyl-benzimidazole complexes with remarkable antibacterial activity

K Chkirate, K Karrouchi, N Dege, NK Sebbar… - New Journal of …, 2020 - pubs.rsc.org
Three mononuclear coordination complexes of 1-butyl-2-((5-methyl-1H-pyrazol-3-yl) methyl)-
1H-benzimidazole (L), namely [CoL] Cl2 (C1),[Co2L2] Cl2· H2O (C2) and [Zn2L2] Cl2 (C3) …

[HTML][HTML] Anticancer activity of Metallodrugs and metallizing host defense peptides—current developments in Structure-Activity relationship

CMC Andrés, JM Pérez de la Lastra… - International Journal of …, 2024 - mdpi.com
This article provides an overview of the development, structure and activity of various metal
complexes with anti-cancer activity. Chemical researchers continue to work on the …

Synthesis, spectroscopic, thermal and molecular modeling studies of Zn2+, Cd2+ and UO22+ complexes of Schiff bases containing triazole moiety. Antimicrobial …

M Gaber, HA El-Ghamry, SK Fathalla… - Materials Science and …, 2018 - Elsevier
A novel series of Zn 2+, Cd 2+ and UO 2 2+ complexes of ligands namely 1-[(5-mercapto-1H-
1, 2, 4-triazole-3-ylimino) methyl] naphthalene-2-ol (HL 1) and [(1H-1, 2, 4-triazole-3-ylimino) …

Current and future potential of metallo drugs: Revisiting DNA-binding of metal containing molecules and their diverse mechanism of action

M Zaki, F Arjmand, S Tabassum - Inorganica Chimica Acta, 2016 - Elsevier
Cancer treatments regimes which include conventional chemotherapy have not proved so
successful in curing human malignancies. Failures to these treatment modalities include …