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Physical activity promotes brain development through serotonin during early childhood
JQ **g, SJ Jia, CJ Yang - Neuroscience, 2024 - Elsevier
Early childhood serves as a critical period for neural development and skill acquisition when
children are extremely susceptible to the external environment and experience. As a crucial …
children are extremely susceptible to the external environment and experience. As a crucial …
Therapeutic mechanisms of psychedelics and entactogens
Recent clinical and preclinical evidence suggests that psychedelics and entactogens may
produce both rapid and sustained therapeutic effects across several indications. Currently …
produce both rapid and sustained therapeutic effects across several indications. Currently …
Modulation of 5-HT release by dynorphin mediates social deficits during opioid withdrawal
Social isolation during opioid withdrawal is a major contributor to the current opioid
addiction crisis. We find that sociability deficits during protracted opioid withdrawal in mice …
addiction crisis. We find that sociability deficits during protracted opioid withdrawal in mice …
Neural circuits regulating prosocial behaviors
Positive, prosocial interactions are essential for survival, development, and well-being.
These intricate and complex behaviors are mediated by an amalgamation of neural circuit …
These intricate and complex behaviors are mediated by an amalgamation of neural circuit …
Context-specific functions of chromatin remodellers in development and disease
Chromatin remodellers were once thought to be highly redundant and nonspecific in their
actions. However, recent human genetic studies demonstrate remarkable biological …
actions. However, recent human genetic studies demonstrate remarkable biological …
Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders
A Annamneedi, C Gora, A Dudas… - British journal of …, 2023 - Wiley Online Library
Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two
core symptoms: deficits in social interaction and communication, and stereotyped …
core symptoms: deficits in social interaction and communication, and stereotyped …
MDMA enhances empathy-like behaviors in mice via 5-HT release in the nucleus accumbens
MDMA (3, 4-methylenedioxymethamphetamine) is a psychoactive drug with powerful
prosocial effects. While MDMA is sometimes termed an “empathogen,” empirical studies …
prosocial effects. While MDMA is sometimes termed an “empathogen,” empirical studies …
Metformin Alleviates Autistic‐Like Behaviors Elicited by High‐Fat Diet Consumption and Modulates the Crosstalk Between Serotonin and Gut Microbiota in Mice
W Deng, H Ke, S Wang, Z Li, S Li, P Lv… - Behavioural …, 2022 - Wiley Online Library
The biological mechanisms linking diet‐related obesity and autistic behaviors remain
unclear. Metformin has proven to be beneficial in the treatment of many syndromes …
unclear. Metformin has proven to be beneficial in the treatment of many syndromes …
FPT, a 2-Aminotetralin, Is a Potent Serotonin 5-HT1A, 5-HT1B, and 5-HT1D Receptor Agonist That Modulates Cortical Electroencephalogram Activity in Adult Fmr1 …
There are no approved medicines for fragile X syndrome (FXS), a monogenic,
neurodevelopmental disorder. Electroencephalogram (EEG) studies show alterations in …
neurodevelopmental disorder. Electroencephalogram (EEG) studies show alterations in …
Attenuation of Autism-like Behaviors by an Anthocyanin-Rich Extract from Portuguese Blueberries via Microbiota–Gut–Brain Axis Modulation in a Valproic Acid Mouse …
D Serra, JF Henriques, FJ Sousa, M Laranjo… - International Journal of …, 2022 - mdpi.com
Autism Spectrum Disorders (ASDs) are a group of neurodevelopmental pathologies whose
current treatment is neither curative nor effective. Anthocyanins are naturally occurring …
current treatment is neither curative nor effective. Anthocyanins are naturally occurring …