Due to the rapid proliferation of tumors, the hydrogen peroxide (H 2 O 2) concentration of
tumor cells is higher than that of normal cells, which can be used as an effective target for …

In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …

Lack of sufficient cytotoxic T lymphocytes (CD8+ T cells) infiltration and dysfunctional state of
CD8+ T cells are considered enormous obstacles to antitumor immunity. Herein, we …

Recently, various metal peroxide nanomaterials have drawn increasing attention as an
efficient hydrogen peroxide (H2O2) self-supplying agent for enhanced tumor therapy …

Bacterial infections remain the leading cause of death worldwide today. The emergence of
antibiotic resistance has urged the development of alternative antibacterial technologies to …

Current chemodynamic therapy (CDT) primarily relies on the delivery of transition metal ions
with Fenton activity to trigger hydroxyl radical production from hydrogen peroxide. However …

Metal peroxide nanoparticles designed to elevate the oxidative stress are considered a
promising nanotherapeutics in biomedical applications, including chemotherapy …

Theranostic nanoplatforms integrating diagnostic and therapeutic functions have received
considerable attention in the past decade. Among them, hollow manganese (Mn)-based …

Emerging noninvasive treatments, such as sonodynamic therapy (SDT) and chemodynamic
therapy (CDT), have developed as promising alternatives or supplements to traditional …

Mitochondria play critical roles in the regulation of the proliferation and apoptosis of
cancerous cells. Targeted induction of mitochondrial dysfunction in cancer cells by …