Tight coupling between biochemical and mechanical properties of the actin cytoskeleton
drives a large range of cellular processes including polarity establishment, morphogenesis …

Organisms from all domains of life depend on filaments of the protein actin to provide
structure and to support internal movements. Many eukaryotic cells use forces produced by …

Rho GTPases are a family of small G proteins that regulate a wide array of cellular
processes related to their key roles controlling the cytoskeleton. Cancer is a multistep …

Cell migration requires sustained forward movement of the plasma membrane at the cell's
front or" leading edge." To date, researchers have uncovered four distinct ways of extending …

The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

Rho GTPases are well known for their roles in regulating cell migration, and also contribute
to a variety of other cellular responses. They are subdivided into 2 groups: typical and …

Membrane protrusions at the leading edge of cells, known as lamellipodia, drive cell
migration in many normal and pathological situations. Lamellipodial protrusion is powered …

Phagocytosis is a remarkably complex and versatile process: it contributes to innate
immunity through the ingestion and elimination of pathogens, while also being central to …

Cell migration is an essential process, both in unicellular organisms such as amoeba and as
individual or collective motility in highly developed multicellular organisms like mammals. It …

Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS),
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are …