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Melt extrusion with poorly soluble drugs–An integrated review
Over the last few decades, hot melt extrusion (HME) has emerged as a successful
technology for a broad spectrum of applications in the pharmaceutical industry. As indicated …
technology for a broad spectrum of applications in the pharmaceutical industry. As indicated …
[HTML][HTML] Hot-melt extrusion in the pharmaceutical industry: toward filing a new drug application
MF Simões, RMA Pinto, S Simões - Drug Discovery Today, 2019 - Elsevier
The pharmaceutical development of amorphous solid dispersions (ASDs) by hot-melt
extrusion (HME) is briefly reviewed. A systematic step-by-step approach is presented, where …
extrusion (HME) is briefly reviewed. A systematic step-by-step approach is presented, where …
Hydroxypropyl methylcellulose-based controlled release dosage by melt extrusion and 3D printing: Structure and drug release correlation
The objective of this study was to develop a new approach for fabrication of zero order
release of active pharmaceutical ingredients (APIs) using hot-melt extrusion (HME) and 3D …
release of active pharmaceutical ingredients (APIs) using hot-melt extrusion (HME) and 3D …
Hot melt extrusion paired fused deposition modeling 3D printing to develop hydroxypropyl cellulose based floating tablets of cinnarizine
Three-dimensional printing could serve as a platform to fabricate individualized medicines
and complex-structured solid dosage forms. Herein, hot melt extrusion was coupled with 3D …
and complex-structured solid dosage forms. Herein, hot melt extrusion was coupled with 3D …
Hot-melt extrusion: Highlighting recent advances in pharmaceutical applications
Hot-melt extrusion (HME) has emerged as a pioneering manufacturing technology for
pharmaceutical industries, and the utilization is overgrowing due to its unit operation, cost …
pharmaceutical industries, and the utilization is overgrowing due to its unit operation, cost …
Hot melt extrusion: Highlighting physicochemical factors to be investigated while designing and optimizing a hot melt extrusion process
Hot-melt extrusion (HME) is a well-accepted and extensively studied method for preparing
numerous types of drug delivery systems and dosage forms. It offers several advantages: no …
numerous types of drug delivery systems and dosage forms. It offers several advantages: no …
Advanced polymers and recent advancements on gastroretentive drug delivery system; a comprehensive review
Oral route of drug administration is typically the initial option for drug administration because
it is both practical and affordable. However, major drawback of this route includes the …
it is both practical and affordable. However, major drawback of this route includes the …
Fabrication of high drug loading levetiracetam tablets using semi-solid extrusion 3D printing
The present study was designed to appraise the superiority of semi-solid extrusion 3D
printing technology in the fabrication of high drug loading (96% w/w) levetiracetam tablets …
printing technology in the fabrication of high drug loading (96% w/w) levetiracetam tablets …
Development and evaluation of an oral fast disintegrating anti-allergic film using hot-melt extrusion technology
The main objective of this novel study was to develop chlorpheniramine maleate orally
disintegrating films (ODF) using hot-melt extrusion technology and evaluate the …
disintegrating films (ODF) using hot-melt extrusion technology and evaluate the …
Formulation development and characterization of dual drug loaded hot-melt extruded inserts for better ocular therapeutic outcomes: Sulfacetamide/prednisolone
The present investigation was intended to formulate and evaluate a hot-melt extruded (HME)
bioadhesive ophthalmic inserts containing a fixed-dose combination of Prednisolone …
bioadhesive ophthalmic inserts containing a fixed-dose combination of Prednisolone …