Programmed and self-organized flow of information during morphogenesis

C Collinet, T Lecuit - Nature Reviews Molecular Cell Biology, 2021 - nature.com
How the shape of embryos and organs emerges during development is a fundamental
question that has fascinated scientists for centuries. Tissue dynamics arise from a small set …

Orchestrating morphogenesis: building the body plan by cell shape changes and movements

KZ Perez-Vale, M Peifer - Development, 2020 - journals.biologists.com
During embryonic development, a simple ball of cells re-shapes itself into the elaborate
body plan of an animal. This requires dramatic cell shape changes and cell movements …

The pulse of morphogenesis: actomyosin dynamics and regulation in epithelia

H Miao, JT Blankenship - Development, 2020 - journals.biologists.com
Actomyosin networks are some of the most crucial force-generating components present in
develo** tissues. The contractile forces generated by these networks are harnessed …

Establishing compartment boundaries in Drosophila wing imaginal discs: An interplay between selector genes, signaling pathways and cell mechanics

J Wang, C Dahmann - Seminars in cell & developmental biology, 2020 - Elsevier
The partitioning of cells into groups or 'compartments' separated by straight and sharp
boundaries is important for tissue formation in animal development. Cells from neighboring …

Cell sorting and morphogenesis in early Drosophila embryos

TE Sharrock, B Sanson - Seminars in Cell & Developmental Biology, 2020 - Elsevier
The regionalisation of growing tissues into compartments that do not mix is thought to be a
common motif of animal development. Compartments and compartmental boundaries were …

Planar Cell Polarity and E-Cadherin in Tissue-Scale Shape Changes in Drosophila Embryos

D Kong, J Großhans - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
Planar cell polarity and anisotropic cell behavior play critical roles in large-scale epithelial
morphogenesis, homeostasis, wound repair, and regeneration. Cell–Cell communication …

Towards a general framework for spatio-temporal transcriptomics

JP Lis, P Villoutreix, T Artières - LMRL Workshop-NeurIPS 2020, 2020 - hal.science
Position and dynamics of cells are essential pieces of information for the study of embryonic
development. Unfortunately, this information is lost in many cell gene expression analysis …

Adhesion dynamics regulate cell intercalation behaviour in an active tissue

A Nestor-Bergmann, GB Blanchard, N Hervieux… - bioRxiv, 2021 - biorxiv.org
Cell intercalation is a key cell behaviour of morphogenesis and wound healing, where local
cell neighbour exchanges can cause dramatic tissue deformations such as body axis …