Rising bacterial antibiotic resistance is a global threat. To deal with it, new antibacterial
agents and antiseptic materials need to be developed. One alternative in this quest is the …

Bactericidal antibiotics kill bacteria by perturbing various cellular targets and processes.
Disruption of the primary antibiotic-binding partner induces a cascade of molecular events …

Bactericidal antibiotics can cause metabolic perturbations that contribute to antibiotic-
induced lethality. The molecular mechanism underlying these downstream effects remains …

A new hybridization of berberine and benzimidazoles was performed to produce 13-
(benzimidazolylmethyl) berberines (BMB) as potentially broad-spectrum antibacterial agents …

Chronic wound infections are one of the major causes of clinical complexities and contribute
to the ever increasing burden on the health care system in low and middle income countries …

Free radical generation plays a key role in killing bacteria by antibiotics. However, radicals
are short-lived and reactive, and thus difficult to detect for the state of the art. Here we use a …

Accurate detection of bacterial antibiotic sensitivity is crucial for theranostics and the
containment of antibiotic-resistant infections. However, the intricate task of detecting and …

Innovative therapeutic approaches are required to battle the rise of antibiotic-resistant
bacterial strains. Tap** on reactive oxygen species (ROS) generation in bacteria induced …

The pressure of antimicrobial resistance has forced many countries to reduce or even
prohibit the use of antibiotics in feed. Therefore, it is an urgent need to develop alternatives …

How double-membraned Gram-negative bacteria overcome lipid peroxidation is virtually
unknown. Bactericidal antibiotics and superoxide ion stress stimulate the transcription of the …