Microbial biomanufacturing is a promising approach to produce high-value compounds with
low-carbon footprint and significant economic benefits. Among twelve “Top Value-Added …

As an alternative to petrochemical synthesis, well-established industrial microbes, such as
Escherichia coli, are employed to produce a wide range of chemicals, including dicarboxylic …

Abstract Itaconic acid (IA), or 2-methylenesuccinic acid, has a broad spectrum of
applications in the biopolymer industry owing to the presence of one vinyl bond and two acid …

Background Itaconic acid, an unsaturated C5 dicarbonic acid, has significant market
demand and prospects. It has numerous biological functions, such as anti-cancer, anti …

For the development of the efficient bio-refinery process or biochemical producer, metabolic
engineering has become an attractive choice recently. However, engineered metabolic …

Biosynthesis of itaconic acid occurs through decarboxylation of the TCA cycle intermediate
cis-aconitate. Engineering of efficient itaconate producers often requires elimination of the …

Simple Summary Biotechnology involves the use of living organisms to create high-value
products. Bacteria and yeast, in particular, are widely applied for such processes, but they …

Introduction Increasing temperature and elevated atmospheric carbon dioxide levels could
impact the survival of stress-adapted bacteria. Method and results In this study, RNA …

Itaconate is a conjugated 1, 4-dicarboxylate produced by macrophages. This small molecule
has recently received increasing attention due to its role in modulating the immune response …

The production of polymers in the present society has relied heavily on fossil resources. It is
not impossible to imagine the world without plastic-based materials. The production of …