Medicinal significance of sp2/sp3 hybridized at C-3-substituted indole-containing lead molecules and FDA-approved drugs
Herein, the privilege in favor of biological importance of indole-containing scaffolds related
to the semi-synthetic and extracted from natural sources is summarized. Such compounds …
to the semi-synthetic and extracted from natural sources is summarized. Such compounds …
A Perspective of the Amide Group Containing FDA Approved Anticancer Drugs from 2021–2022 (A Review)
M Asif, R Srivastava, A Fatima, M Shakeel… - Russian Journal of …, 2023 - Springer
In this review, we describe a collection and assessment of 16 anticancer drugs approved by
the US FDA between 2021 to June 2022, which include small and big amide group …
the US FDA between 2021 to June 2022, which include small and big amide group …
Novel functionalized spiro [Indoline-3, 5′-pyrroline]-2, 2′ dione derivatives: synthesis, characterization, drug-likeness, ADME, and anticancer potential
A highly stereo-selective, one-pot, multicomponent method was chosen to synthesize the
novel functionalized 1, 3-cycloaddition spirooxindoles (SOXs)(4a–4h). Synthesized SOXs …
novel functionalized 1, 3-cycloaddition spirooxindoles (SOXs)(4a–4h). Synthesized SOXs …
Designing, Characterization, DFT, Biological Effectiveness, and Molecular Docking Analysis of Novel Fe(III), Co(II), and Cu(II) Complexes Based on 4-Hydroxy-2H-pyrano[3,2-c] …
The main target of the current framework is the designing and synthesizing of novel iron (III),
cobalt (II), and cupper (II) complex compounds emanating from bioactive nucleus, 4-hydroxy …
cobalt (II), and cupper (II) complex compounds emanating from bioactive nucleus, 4-hydroxy …
Evaluation of N80 Carbon Steel Corrosion in 15 wt.% HCl Using Isatin-hydrazones: A Comprehensive Approach with Chemical, Electrochemical Techniques, and …
The adverse effects of corrosion on industrial metals, particularly N80 carbon steel under
acidic conditions, call for develo** effective corrosion inhibitors. Due to their structural and …
acidic conditions, call for develo** effective corrosion inhibitors. Due to their structural and …
Indolin-2-one derivatives as corrosion inhibitors: Structural insights and evaluation through experimental and computational techniques
Effective corrosion management is a pivotal challenge facing various industries and holds
crucial importance in aligning industrial processes with sustainability goals. This study …
crucial importance in aligning industrial processes with sustainability goals. This study …
Investigation of substituent effects on the electronic structure and antiviral activity of favipiravir derivatives for Covid-19 treatment using DFT and molecular docking
In this study, Density-functional theory/Time-dependent density-functional theory
(DFT/TDDFT) and Molecular docking method was used to investigate the effect of methyl …
(DFT/TDDFT) and Molecular docking method was used to investigate the effect of methyl …
Synthesis, characterization, pharmaceutical evaluation, molecular docking and DFT calculations of a novel drug (E)-5-bromo-3-(phenylimino) indolin-2-one
Herein, one-pot synthesis of (E)-5-bromo-3-(phenylimino) indolin-2-one (5BPI molecule),
density function theory for validation of the synthesized molecule, and biological activities …
density function theory for validation of the synthesized molecule, and biological activities …
Importance of solvent roles in molecular, electronic and dynamical properties, thermodynamic quantities, Mulliken charges, reactive analysis and molecular docking of …
Abstract The 2-Bromo-1H-imidazole-4, 5-dicarbonitrile (2B1HID) molecule is studied by
quantum mechanical and vibrational spectroscopic methods. Atoms In Molecules (AIM) was …
quantum mechanical and vibrational spectroscopic methods. Atoms In Molecules (AIM) was …
[HTML][HTML] Comprehensive analysis of (E)-3-(4-chlorophenyl)-1-(4-methoxyphenyl) prop-2-en-1-one (4CP4MPO): synthesis, Spectroscopic, salvation electronic …
The investigation into a prospective pharmaceutical chalcone derivative employs a
comprehensive methodology, integrating theoretical and empirical analyses. Rigorous …
comprehensive methodology, integrating theoretical and empirical analyses. Rigorous …