Tuberculosis (TB) is the number one cause of human death due to an infectious disease.
The causative agents of TB are a group of closely related bacteria known as the …

The causative agent of human tuberculosis, Mycobacterium tuberculosis complex (MTBC),
comprises seven phylogenetically distinct lineages associated with different geographical …

Taxonomy is an organizing principle of biology and is ideally based on evolutionary
relationships among organisms. Development of a robust bacterial taxonomy has been …

The emerging global infectious COVID-19 disease by novel Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) presents critical threats to global public health and …

Generalist and specialist species differ in the breadth of their ecological niches. Little is
known about the niche width of obligate human pathogens. Here we analyzed a global …

Strain-specific genomic diversity in the Mycobacterium tuberculosis complex (MTBC) is an
important factor in pathogenesis that may affect virulence, transmissibility, host response …

Mycobacterium tuberculosis strains of the Bei**g lineage are globally distributed and are
associated with the massive spread of multidrug-resistant (MDR) tuberculosis in Eurasia …

The causative agent of human tuberculosis (TB), M ycobacterium tuberculosis, is an obligate
pathogen that evolved to exclusively persist in human populations. For M. tuberculosis to …

Epidemics of drug-resistant bacteria emerge worldwide, even as resistant strains frequently
have reduced fitness compared to their drug-susceptible counterparts. Data from model …

The rapid identification of antimicrobial resistance is essential for effective treatment of
highly resistant Mycobacterium tuberculosis. Whole-genome sequencing provides …