Aging, obesity, sarcopenia and the effect of diet and exercise intervention

G Colleluori, DT Villareal - Experimental Gerontology, 2021 - Elsevier
The number of adults 65 years and older is increasing worldwide and will represent the 20%
of the population by 2030. Half of them will suffer from obesity. The decline in muscle mass …

Reduced physical activity in young and older adults: metabolic and musculoskeletal implications

KA Bowden Davies, S Pickles… - Therapeutic …, 2019 - journals.sagepub.com
Background: Although the health benefits of regular physical activity and exercise are well
established and have been incorporated into national public health recommendations, there …

Protein content and amino acid composition of commercially available plant-based protein isolates

SHM Gorissen, JJR Crombag, JMG Senden… - Amino acids, 2018 - Springer
The postprandial rise in essential amino acid (EAA) concentrations modulates the increase
in muscle protein synthesis rates after protein ingestion. The EAA content and AA …

Sarcopenic obesity: time to meet the challenge

R Barazzoni, S Bischoff, Y Boirie, L Busetto… - Obesity facts, 2018 - karger.com
The prevalence of overweight and obesity has reached epidemic proportions worldwide due
to increasingly pervasive obesogenic lifestyle changes. Obesity poses unprecedented …

The anabolic response to plant-based protein ingestion

PJM Pinckaers, J Trommelen, T Snijders… - Sports Medicine, 2021 - Springer
There is a global trend of an increased interest in plant-based diets. This includes an
increase in the consumption of plant-based proteins at the expense of animal-based …

The role of the IGF-1 signaling cascade in muscle protein synthesis and anabolic resistance in aging skeletal muscle

RD Barclay, NA Burd, C Tyler, NA Tillin… - Frontiers in …, 2019 - frontiersin.org
Sarcopenia is defined as the combined loss of skeletal muscle strength, function, and/or
mass with aging. This degenerative loss of muscle mass is associated with poor quality of …

Anabolic resistance of muscle protein turnover comes in various shapes and sizes

KJM Paulussen, CF McKenna, JW Beals… - Frontiers in …, 2021 - frontiersin.org
Anabolic resistance is defined by a blunted stimulation of muscle protein synthesis rates
(MPS) to common anabolic stimuli in skeletal muscle tissue such as dietary protein and …

[HTML][HTML] Food-first approach to enhance the regulation of post-exercise skeletal muscle protein synthesis and remodeling

NA Burd, JW Beals, IG Martinez, AF Salvador… - Sports medicine, 2019 - Springer
Protein recommendations are provided on a daily basis as defined by the recommended
dietary allowance (RDA) at 0.80 g protein/kg/day. However, meal-based, as opposed to …

Muscle and bone health in postmenopausal women: role of protein and vitamin D supplementation combined with exercise training

D Agostini, S Donati Zeppa, F Lucertini, G Annibalini… - Nutrients, 2018 - mdpi.com
Menopause is an age-dependent physiological condition associated with a natural decline
in oestrogen levels, which causes a progressive decrease of muscle mass and strength and …

Double burden of malnutrition in persons with obesity

R Barazzoni, G Gortan Cappellari - Reviews in Endocrine and Metabolic …, 2020 - Springer
A paradoxical double challenge has emerged in the last decades with respect to nutrition
and nutrition-related clinical conditions. Hunger-related undernutrition continues to …