L-carnitine and acylcarnitines: mitochondrial biomarkers for precision medicine

MR McCann, MV George De la Rosa, GR Rosania… - Metabolites, 2021 - mdpi.com
Biomarker discovery and implementation are at the forefront of the precision medicine
movement. Modern advances in the field of metabolomics afford the opportunity to readily …

Machine learning: a new prospect in multi-omics data analysis of cancer

B Arjmand, SK Hamidpour, A Tayanloo-Beik… - Frontiers in …, 2022 - frontiersin.org
Cancer is defined as a large group of diseases that is associated with abnormal cell growth,
uncontrollable cell division, and may tend to im**e on other tissues of the body by different …

Role of GATA3 in tumor diagnosis: A review

MK Najafabadi, E Mirzaeian, SM Montazerin… - … -Research and Practice, 2021 - Elsevier
Abstract GATA binding protein 3 (GATA3) belongs to a family of transcription factors
comprising six members. These proteins identify GATA containing sequences in the target …

Mass spectrometry-based metabolomics for clinical study: Recent progresses and applications

J Ding, YQ Feng - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
In clinical study, metabolomics aims to characterize the metabolic disturbance at the disease
state using large cohorts and further provides diagnostic evidence at the small molecular …

Metabolic rewiring and the characterization of oncometabolites

D Beyoğlu, JR Idle - Cancers, 2021 - mdpi.com
Simple Summary Oncometabolites are produced by cancer cells and assist the cancer to
proliferate and progress. Oncometabolites occur as a result of mutated enzymes in the tumor …

Systems biomarkers for papillary thyroid cancer prognosis and treatment through multi-omics networks

G Gulfidan, M Soylu, D Demirel, HBC Erdonmez… - Archives of biochemistry …, 2022 - Elsevier
The identification of biomolecules associated with papillary thyroid cancer (PTC) has upmost
importance for the elucidation of the disease mechanism and the development of effective …

Malignant and benign thyroid nodule differentiation through the analysis of blood plasma with terahertz spectroscopy

MR Konnikova, OP Cherkasova… - Biomedical Optics …, 2021 - opg.optica.org
The liquid and lyophilized blood plasma of patients with benign or malignant thyroid nodules
and healthy individuals were studied by terahertz (THz) time-domain spectroscopy and …

LC/MS-based polar metabolite profiling identified unique biomarker signatures for cervical cancer and cervical intraepithelial neoplasia using global and targeted …

I Khan, M Nam, M Kwon, S Seo, S Jung, JS Han… - Cancers, 2019 - mdpi.com
Cervical cancer remains one of the most prevalent cancers among females worldwide.
Therefore, it is important to discover new biomarkers for early diagnosis of cervical …

OMICS insights into cancer histology; Metabolomics and proteomics approach

A Tayanloo-Beik, M Sarvari, M Payab, K Gilany… - Clinical …, 2020 - Elsevier
Metabolomics as a post-genomic research area comprising different analytical methods for
small molecules analysis. One of the underlying applications of metabolomics technology for …

Evolutionary view on lactate-dependent mechanisms of maintaining cancer cell stemness and reprimitivization

PV Shegay, AA Zabolotneva, OP Shatova… - Cancers, 2022 - mdpi.com
Simple Summary For a long-time lactic acid has been considered as a toxic end-product of
metabolism that cause different adverse effects. However, in recent decades a plenty of …