We propose a novel approach to background correction for Infinium HumanMethylation data
to account for technical variation in background fluorescence signal. Our approach …

In this paper, we present the results of the research concerning extraction of informative
gene expression profiles from high-dimensional array of gene expressions considering the …

The advent of high-throughput next generation sequencing technologies have fostered
enormous potential applications of supercomputing techniques in genome sequencing, epi …

The paper presents the comparison analysis of various techniques of DNA microarrays data
pre-processing in order to choose the optimal combination of the methods in terms of the …

In this paper, we have presented a results of the research concerning selection of
informative genes based on the complex use of both statistical criteria and Shannon entropy …

Bioinformatics and systems biology are two booming research areas studying live
organisms. Though having different focuses, bioinformatics and systems biology often share …

One important purpose to investigate medicinal plants is to understand genes and enzymes
that govern the biological metabolic process to produce bioactive compounds. Genome …

Background In microarray experiments with small sample sizes, it is a challenge to estimate
p-values accurately and decide cutoff p-values for gene selection appropriately. Although …

Results: The obtained results in this study showed that most of the genes that had a
significant increase in expression level were associated with the innate immune system …

Background One important preprocessing step in the analysis of microarray data is
background subtraction. In high-density oligonucleotide arrays this is recognized as a …