Monoclonal antibodies constitute a promising class of targeted anticancer agents that
enhance natural immune system functions to suppress cancer cell activity and eliminate …

Today, bio-medical efforts are entering the subcellular level, which is witnessed with the fast-
develo** fields of nanomedicine, nanodiagnostics and nanotherapy in conjunction with …

Highlights•Nanobodies (Nbs) are camelid-derived single-domain antibodies.•Nbs have
powerful binding and inhibitory capacity with great therapeutic potential.•Nbs are used in …

Since the licensing of the first monoclonal antibody therapy in 1986, monoclonal antibodies
have become the largest class of biopharmaceuticals with over 80 antibodies currently …

Nanobodies can be seen as next‐generation tools for the recognition and modulation of
antigens that are inaccessible to conventional antibodies. Due to their compact structure and …

Molecular imaging involves the non-invasive investigation of biological processes in vivo at
the cellular and molecular level, which can play diverse roles in better understanding and …

Targeted protein degradation (TPD) has emerged in the past decade as a major new drug
modality to remove intracellular proteins with bispecific small molecules that recruit the …

Since their discovery, nanobodies have been used extensively in the fields of research,
diagnostics and therapy. These antigen binding fragments, originating from Camelid heavy …

For treatment and diagnosis of cancer, antibodies have proven their value and now serve as
a first line of therapy for certain cancers. A unique class of antibody fragments called …

Targeted therapy and immunotherapy have become mainstream in cancer treatment.
However, only patient subsets benefit from these expensive therapies, and often responses …