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Cancer cell plasticity during tumor progression, metastasis and response to therapy
Cell plasticity represents the ability of cells to be reprogrammed and to change their fate and
identity, enabling homeostasis restoration and tissue regeneration following damage. Cell …
identity, enabling homeostasis restoration and tissue regeneration following damage. Cell …
Cancer stem cells: Advances in knowledge and implications for cancer therapy
Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …
Genetic and biological hallmarks of colorectal cancer
Colorectal cancer has served as a genetic and biological paradigm for the evolution of solid
tumors, and these insights have illuminated early detection, risk stratification, prevention …
tumors, and these insights have illuminated early detection, risk stratification, prevention …
Hallmarks of cancer stemness
Cancer stemness is recognized as a key component of tumor development. Previously
coined" cancer stem cells"(CSCs) and believed to be a rare population with rigid …
coined" cancer stem cells"(CSCs) and believed to be a rare population with rigid …
Exploring the dynamic interplay between cancer stem cells and the tumor microenvironment: implications for novel therapeutic strategies
Cancer stem cells (CSCs) have emerged as key contributors to tumor initiation, growth, and
metastasis. In addition, CSCs play a significant role in inducing immune evasion, thereby …
metastasis. In addition, CSCs play a significant role in inducing immune evasion, thereby …
Osteosarcoma: a review of current and future therapeutic approaches
X Zhao, Q Wu, X Gong, J Liu, Y Ma - Biomedical engineering online, 2021 - Springer
Osteosarcoma (OS) is the most common primary bone malignancy that affects children and
young adults. OS is characterized by a high degree of malignancy, strong invasiveness …
young adults. OS is characterized by a high degree of malignancy, strong invasiveness …
Stem cell programs in cancer initiation, progression, and therapy resistance
Over the past few decades, substantial evidence has convincingly revealed the existence of
cancer stem cells (CSCs) as a minor subpopulation in cancers, contributing to an aberrantly …
cancer stem cells (CSCs) as a minor subpopulation in cancers, contributing to an aberrantly …
Cancer stem cells revisited
The cancer stem cell (CSC) concept was proposed four decades ago, and states that tumor
growth, analogous to the renewal of healthy tissues, is fueled by small numbers of dedicated …
growth, analogous to the renewal of healthy tissues, is fueled by small numbers of dedicated …
Brain cancer stem cells: resilience through adaptive plasticity and hierarchical heterogeneity
Malignant brain tumours are complex ecosystems containing neoplastic and stromal
components that generate adaptive and evolutionarily driven aberrant tissues in the central …
components that generate adaptive and evolutionarily driven aberrant tissues in the central …
Cancer stem cell (CSC) resistance drivers
Cancer stem cells (CSCs) are a population of self-renewal cells with high tumorigenic
potency. CSCs can adopt easily with changes in the nearby milieu, and are more resistant to …
potency. CSCs can adopt easily with changes in the nearby milieu, and are more resistant to …