Phase reduction and phase-based optimal control for biological systems: a tutorial
A powerful technique for the analysis of nonlinear oscillators is the rigorous reduction to
phase models, with a single variable describing the phase of the oscillation with respect to …
phase models, with a single variable describing the phase of the oscillation with respect to …
Control and synchronization of neuron ensembles
Synchronization of oscillations is a phenomenon prevalent in natural, social, and
engineering systems. Controlling synchronization of oscillating systems is motivated by a …
engineering systems. Controlling synchronization of oscillating systems is motivated by a …
Optimal chaotic desynchronization for neural populations
A procedure is developed for finding an energy-optimal stimulus which gives a positive
Lyapunov exponent, and hence desynchronization, for a neural population. The procedure …
Lyapunov exponent, and hence desynchronization, for a neural population. The procedure …
Minimum energy desynchronizing control for coupled neurons
We employ optimal control theory to design an event-based, minimum energy,
desynchronizing control stimulus for a network of pathologically synchronized …
desynchronizing control stimulus for a network of pathologically synchronized …
Single input optimal control for globally coupled neuron networks
We consider the problem of desynchronizing a network of synchronized, globally (all-to-all)
coupled neurons using an input to a single neuron. This is done by applying the discrete …
coupled neurons using an input to a single neuron. This is done by applying the discrete …
Stochastic optimal control of single neuron spike trains
A Iolov, S Ditlevsen, A Longtin - Journal of neural engineering, 2014 - iopscience.iop.org
Objective. External control of spike times in single neurons can reveal important information
about a neuron's sub-threshold dynamics that lead to spiking, and has the potential to …
about a neuron's sub-threshold dynamics that lead to spiking, and has the potential to …
Minimum energy control for in vitro neurons
Objective. To demonstrate the applicability of optimal control theory for designing minimum
energy charge-balanced input waveforms for single periodically-firing in vitro neurons from …
energy charge-balanced input waveforms for single periodically-firing in vitro neurons from …
Time optimal control of spiking neurons
By injecting an electrical current control stimulus into a neuron, one can change its inter-
spike intervals. In this paper, we investigate the time optimal control problem for periodically …
spike intervals. In this paper, we investigate the time optimal control problem for periodically …
Locally optimal extracellular stimulation for chaotic desynchronization of neural populations
We use optimal control theory to design a methodology to find locally optimal stimuli for
desynchronization of a model of neurons with extracellular stimulation. This methodology …
desynchronization of a model of neurons with extracellular stimulation. This methodology …
Constrained charge-balanced minimum-power controls for spiking neuron oscillators
In this paper, we study the optimal control of phase models for spiking neuron oscillators. We
focus on the design of minimum-power current stimuli that elicit spikes of neurons at …
focus on the design of minimum-power current stimuli that elicit spikes of neurons at …