[HTML][HTML] Biomedical applications of microfluidic devices: a review

G Gharib, İ Bütün, Z Muganlı, G Kozalak, İ Namlı… - Biosensors, 2022‏ - mdpi.com
Both passive and active microfluidic chips are used in many biomedical and chemical
applications to support fluid mixing, particle manipulations, and signal detection. Passive …

Microfluidic chips: recent advances, critical strategies in design, applications and future perspectives

P Pattanayak, SK Singh, M Gulati, S Vishwas… - Microfluidics and …, 2021‏ - Springer
Microfluidic chip technology is an emerging tool in the field of biomedical application.
Microfluidic chip includes a set of groves or microchannels that are engraved on different …

Foundations of gastrointestinal-based drug delivery and future developments

JN Chu, G Traverso - Nature Reviews Gastroenterology & Hepatology, 2022‏ - nature.com
Gastrointestinal-based drug delivery is considered the preferred mode of drug
administration owing to its convenience for patients, which improves adherence. However …

[HTML][HTML] Organs-on-chips technologies–A guide from disease models to opportunities for drug development

AG Monteduro, S Rizzato, G Caragnano… - Biosensors and …, 2023‏ - Elsevier
Current in-vitro 2D cultures and animal models present severe limitations in recapitulating
human physiopathology with striking discrepancies in estimating drug efficacy and side …

Organ-on-a-chip meets artificial intelligence in drug evaluation

S Deng, C Li, J Cao, Z Cui, J Du, Z Fu, H Yang… - …, 2023‏ - pmc.ncbi.nlm.nih.gov
Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …

[HTML][HTML] Role of the encapsulation in bioavailability of phenolic compounds

J Grgić, G Šelo, M Planinić, M Tišma, A Bucić-Kojić - Antioxidants, 2020‏ - mdpi.com
Plant-derived phenolic compounds have multiple positive health effects for humans
attributed to their antioxidative, anti-inflammatory, and antitumor properties, etc. These …

Microfluidics for drug development: from synthesis to evaluation

Y Liu, L Sun, H Zhang, L Shang, Y Zhao - Chemical reviews, 2021‏ - ACS Publications
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …

Brain-on-a-chip: Recent advances in design and techniques for microfluidic models of the brain in health and disease

L Amirifar, A Shamloo, R Nasiri, NR de Barros… - Biomaterials, 2022‏ - Elsevier
Recent advances in biomaterials, microfabrication, microfluidics, and cell biology have led to
the development of organ-on-a-chip devices that can reproduce key functions of various …

[HTML][HTML] Emerging trends in organ-on-a-chip systems for drug screening

Y Wang, Y Gao, Y Pan, D Zhou, Y Liu, Y Yin… - … Pharmaceutica Sinica B, 2023‏ - Elsevier
New drug discovery is under growing pressure to satisfy the demand from a wide range of
domains, especially from the pharmaceutical industry and healthcare services. Assessment …

[HTML][HTML] The gut–organ-axis concept: advances the application of gut-on-chip technology

Y Guo, X Chen, P Gong, G Li, W Yao… - International Journal of …, 2023‏ - mdpi.com
The intestine is considered to be a vital digestive organ to absorb nutrients and is the largest
immune organ, while numerous microorganisms coexist with the host. It is well known that …