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[HTML][HTML] Role of miRNA-regulated cancer stem cells in the pathogenesis of human malignancies
Recent biomedical discoveries have revolutionized the concept and understanding of
carcinogenesis, a complex and multistep phenomenon which involves accretion of genetic …
carcinogenesis, a complex and multistep phenomenon which involves accretion of genetic …
Cancer-associated miRNAs and their therapeutic potential
J Inoue, J Inazawa - Journal of human genetics, 2021 - nature.com
MicroRNA (miRNA; miR) is a functionally small non-coding RNA and can negatively
regulate gene expression by directly binding to the target gene. Some miRNAs are closely …
regulate gene expression by directly binding to the target gene. Some miRNAs are closely …
[HTML][HTML] Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets
Simple Summary By the virtue of targeting multiple genes, a microRNA (miRNA) can infer
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …
[HTML][HTML] Friend or foe: S100 proteins in cancer
C Allgöwer, AL Kretz, S von Karstedt, M Wittau… - Cancers, 2020 - mdpi.com
S100 proteins are widely expressed small molecular EF-hand calcium-binding proteins of
vertebrates, which are involved in numerous cellular processes, such as Ca2+ homeostasis …
vertebrates, which are involved in numerous cellular processes, such as Ca2+ homeostasis …
[HTML][HTML] MicroRNAs and their big therapeutic impacts: delivery strategies for cancer intervention
C Holjencin, A Jakymiw - Cells, 2022 - mdpi.com
Three decades have passed from the initial discovery of a microRNA (miRNA) in
Caenorhabditis elegans to our current understanding that miRNAs play essential roles in …
Caenorhabditis elegans to our current understanding that miRNAs play essential roles in …
Hsa_circ_0002483 inhibited the progression and enhanced the Taxol sensitivity of non-small cell lung cancer by targeting miR-182-5p
X Li, B Yang, H Ren, T **ao, L Zhang, L Li, M Li… - Cell death & …, 2019 - nature.com
In this study, we identified a novel circRNA, circ_0002483, and further investigated its
functions in the progression and Taxol resistance of NSCLC. We found that circ_0002483 …
functions in the progression and Taxol resistance of NSCLC. We found that circ_0002483 …
Use of microRNAs as diagnostic, prognostic, and therapeutic tools for glioblastoma
Glioblastoma (GB) is the most aggressive and common type of cancer within the central
nervous system (CNS). Despite the vast knowledge of its physiopathology and histology, its …
nervous system (CNS). Despite the vast knowledge of its physiopathology and histology, its …
The current state of MiRNAs as biomarkers and therapeutic tools
I Gareev, O Beylerli, G Yang, J Sun, V Pavlov… - Clinical and …, 2020 - Springer
MicroRNAs (miRNAs) are non-coding RNAs with a length of 18–22 nucleotides that regulate
about a third of the human genome at the post-transcriptional level. MiRNAs are involved in …
about a third of the human genome at the post-transcriptional level. MiRNAs are involved in …
[HTML][HTML] miRacle of microRNA-driven cancer nanotherapeutics
Simple Summary The discovery of microRNAs has revolutionized the world of science and
opened up new opportunities in cancer treatment. miRNA dysregulation plays a crucial role …
opened up new opportunities in cancer treatment. miRNA dysregulation plays a crucial role …
Sensitivity and specificity of microRNA-204, CA125, and CA19. 9 as biomarkers for diagnosis of ovarian cancer
Background Ovarian cancer is usually detected at later stages and no effective screening
approach, has been identified. Therefore, sensitive and specific biomarkers for detecting …
approach, has been identified. Therefore, sensitive and specific biomarkers for detecting …