Fast detection and identification of microorganisms is a challenging and significant feature
from industry to medicine. Standard approaches are known to be very time-consuming and …

Corynebacterium glutamicum is a major workhorse in industrial biotechnology. For the past
several decades, this soil bacterium has been used to produce the amino acids l-glutamate …

Abstract Background Soybean (Glycine max [L.] Merr.) is one of the most important oil and
protein crops. Ever-increasing soybean consumption necessitates the improvement of …

Here, we describe the development of a genetically defined strain of l-lysine hyperproducing
Corynebacterium glutamicum by systems metabolic engineering of the wild type …

Highlights•13 C tracer analysis can be used to probe intracellular metabolism in
cells.•Steady state labeling patterns can quantify nutrient contributions.•Steady state labeling …

Mass spectrometry (MS) is widely used for isotopic labeling studies of metabolism and other
biological processes. Quantitative applications—eg metabolic flux analysis—require tools to …

Polyethylene terephthalate (PET), the most common synthetic polyester today, is largely
produced from fossil resources, contributing to global warming. Consequently, sustainable …

Lignin is nature's second most abundant polymer and displays a largely unexploited
renewable resource for value-added bio-production. None of the lignin-based fermentation …

Background The quantitative analysis of metabolic fluxes, ie, in vivo activities of intracellular
enzymes and pathways, provides key information on biological systems in systems biology …

The genus Pseudomonas comprises approximately 200 species with numerous isolates that
are common inhabitants of soil, water, and vegetation and has been of particular interest for …