CRISPR/Cas systems towards next-generation biosensing

Y Li, S Li, J Wang, G Liu - Trends in biotechnology, 2019 - cell.com
Beyond its remarkable genome editing ability, the CRISPR/Cas9 effector has also been
utilized in biosensing applications. The recent discovery of the collateral RNA cleavage …

Molecular and genetic bases of heat stress responses in crop plants and breeding for increased resilience and productivity

M Janni, M Gullì, E Maestri, M Marmiroli… - Journal of …, 2020 - academic.oup.com
To ensure the food security of future generations and to address the challenge of the 'no
hunger zone'proposed by the FAO (Food and Agriculture Organization), crop production …

Loss of function of a DMR6 ortholog in tomato confers broad-spectrum disease resistance

DPT Thomazella, K Seong, R Mackelprang… - Proceedings of the …, 2021 - pnas.org
Plant diseases are among the major causes of crop yield losses around the world. To confer
disease resistance, conventional breeding relies on the deployment of single resistance (R) …

Mutations introduced in susceptibility genes through CRISPR/Cas9 genome editing confer increased late blight resistance in potatoes

NP Kieu, M Lenman, ES Wang, BL Petersen… - Scientific Reports, 2021 - nature.com
The use of pathogen-resistant cultivars is expected to increase yield and decrease fungicide
use in agriculture. However, in potato breeding, increased resistance obtained via …

[HTML][HTML] Single-cell profiling of Arabidopsis leaves to Pseudomonas syringae infection

J Zhu, S Lolle, A Tang, B Guel, B Kvitko, B Cole… - Cell reports, 2023 - cell.com
Plant response to pathogen infection varies within a leaf, yet this heterogeneity is not well
resolved. We expose Arabidopsis to Pseudomonas syringae or mock treatment and profile> …

[HTML][HTML] Understanding the Dynamics of Blast Resistance in Rice-Magnaporthe oryzae Interactions

BN Devanna, P Jain, AU Solanke, A Das, S Thakur… - Journal of Fungi, 2022 - mdpi.com
Rice is a global food grain crop for more than one-third of the human population and a
source for food and nutritional security. Rice production is subjected to various stresses; …

Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants

SSA Zaidi, A Mahas, H Vanderschuren, MM Mahfouz - Genome biology, 2020 - Springer
To meet increasing global food demand, breeders and scientists aim to improve the yield
and quality of major food crops. Plant diseases threaten food security and are expected to …

Exploiting broad-spectrum disease resistance in crops: from molecular dissection to breeding

W Li, Y Deng, Y Ning, Z He… - Annual review of plant …, 2020 - annualreviews.org
Plant diseases reduce crop yields and threaten global food security, making the selection of
disease-resistant cultivars a major goal of crop breeding. Broad-spectrum resistance (BSR) …

CRISPR technology is revolutionizing the improvement of tomato and other fruit crops

T Wang, H Zhang, H Zhu - Horticulture research, 2019 - academic.oup.com
Fruits are major sources of essential nutrients and serve as staple foods in some areas of
the world. The increasing human population and changes in climate experienced worldwide …

[HTML][HTML] Inactivation of a wheat protein kinase gene confers broad-spectrum resistance to rust fungi

N Wang, C Tang, X Fan, M He, P Gan, S Zhang, Z Hu… - Cell, 2022 - cell.com
Wheat crops are frequently devastated by pandemic stripe rust caused by Puccinia
striiformis f. sp. tritici (Pst). Here, we identify and characterize a wheat receptor-like …