[HTML][HTML] Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit
NA Sims, TJ Martin - BoneKEy reports, 2014 - ncbi.nlm.nih.gov
Coupling between bone formation and bone resorption refers to the process within basic
multicellular units in which resorption by osteoclasts is met by the generation of osteoblasts …
multicellular units in which resorption by osteoclasts is met by the generation of osteoblasts …
Bone remodeling
DJ Hadjidakis, II Androulakis - Annals of the New York academy …, 2006 - Wiley Online Library
The skeleton is a metabolically active organ that undergoes continuous remodeling
throughout life. Bone remodeling involves the removal of mineralized bone by osteoclasts …
throughout life. Bone remodeling involves the removal of mineralized bone by osteoclasts …
Osteoclasts provide coupling signals to osteoblast lineage cells through multiple mechanisms
NA Sims, TJ Martin - Annual review of physiology, 2020 - annualreviews.org
Bone remodeling is essential for the repair and replacement of damaged and old bone. The
major principle underlying this process is that osteoclast-mediated resorption of a quantum …
major principle underlying this process is that osteoclast-mediated resorption of a quantum …
Emerging insights into the comparative effectiveness of anabolic therapies for osteoporosis
EG Estell, CJ Rosen - Nature Reviews Endocrinology, 2021 - nature.com
Over the past three decades, the mainstay of treatment for osteoporosis has been
antiresorptive agents (such as bisphosphonates), which have been effective with continued …
antiresorptive agents (such as bisphosphonates), which have been effective with continued …
Breast cancer bone metastases: pathogenesis and therapeutic targets
N Brook, E Brook, A Dharmarajan, CR Dass… - The international journal …, 2018 - Elsevier
Breast cancer is the most common cancer affecting women worldwide, with bone
metastases presenting as the most common site of disease recurrence. Bone metastases …
metastases presenting as the most common site of disease recurrence. Bone metastases …
Osteoclast-derived activity in the coupling of bone formation to resorption
TJ Martin, NA Sims - Trends in molecular medicine, 2005 - cell.com
The cells of bone and the immune system communicate by means of soluble and membrane-
bound cytokines and growth factors. Through local signalling mechanisms, cells of the …
bound cytokines and growth factors. Through local signalling mechanisms, cells of the …
Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis
LJ Zhao, H Jiang, CJ Papasian, D Maulik… - Journal of bone and …, 2008 - academic.oup.com
It was previously believed that obesity and osteoporosis were two unrelated diseases, but
recent studies have shown that both diseases share several common genetic and …
recent studies have shown that both diseases share several common genetic and …
Effects of inflammatory and anti‐inflammatory cytokines on the bone
G Schett - European journal of clinical investigation, 2011 - Wiley Online Library
Eur J Clin Invest 2011; 41 (12): 1361–1366 Abstract Background Inflammatory diseases are
linked to enhanced bone loss. The effect of inflammation on bone is mediated by …
linked to enhanced bone loss. The effect of inflammation on bone is mediated by …
Identification of salivary microbiota and its association with host inflammatory mediators in periodontitis
Periodontitis is a microbial-induced chronic inflammatory disease, which may not only result
in tooth loss, but can also contribute to the development of various systemic diseases. The …
in tooth loss, but can also contribute to the development of various systemic diseases. The …
The obesity of bone
During the last decades, obesity and osteoporosis have become important global health
problems, and the belief that obesity is protective against osteoporosis has recently come …
problems, and the belief that obesity is protective against osteoporosis has recently come …