[HTML][HTML] Fullerene: biomedical engineers get to revisit an old friend

S Goodarzi, T Da Ros, J Conde, F Sefat, M Mozafari - Materials Today, 2017 - Elsevier
In 1985, the serendipitous discovery of fullerene triggered the research of carbon structures
into the world of symmetric nanomaterials. Consequently, Robert F. Curl, Harold W. Kroto …

Challenges in development of nanoparticle-based therapeutics

N Desai - The AAPS journal, 2012 - Springer
In recent years, nanotechnology has been increasingly applied to the area of drug
development. Nanoparticle-based therapeutics can confer the ability to overcome biological …

Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution

MA Dobrovolskaia, P Aggarwal, JB Hall… - Molecular …, 2008 - ACS Publications
Nanoparticles have unique physicochemical properties which make them promising
platforms for drug delivery. However, immune cells in the bloodstream (such as monocytes …

Biomedical potential of the reactive oxygen species generation and quenching by fullerenes (C60)

Z Markovic, V Trajkovic - Biomaterials, 2008 - Elsevier
Fullerene (C60), a third carbon allotrope, is a classical engineered material with the
potential application in biomedicine. One of the biologically most relevant features of C60 is …

Physicochemical Characterization and In Vitro Hemolysis Evaluation of Silver Nanoparticles

J Choi, V Reipa, VM Hitchins, PL Goering… - Toxicological …, 2011 - academic.oup.com
Silver nanomaterials are increasingly being used as antimicrobial agents in medical
devices. This study assessed the in vitro hemolytic potential of unbound silver particles in …

Biomedical applications of functionalized fullerene-based nanomaterials

R Partha, JL Conyers - International journal of nanomedicine, 2009 - Taylor & Francis
Since their discovery in 1985, fullerenes have been investigated extensively due to their
unique physical and chemical properties. In recent years, studies on functionalized …

Environmental risks of nanotechnology: National nanotechnology initiative funding, 2000− 2004

KA Dunphy Guzmán, MR Taylor, JF Banfield - 2006 - ACS Publications
By considering risk in the early stages of a technology, costs of identifying important health
and environmental impacts after a technology has widely diffused can be avoided …

Fullerenes for the treatment of cancer: an emerging tool

NB Fernandes, RUK Shenoy, MK Kajampady… - … Science and Pollution …, 2022 - Springer
Cancer is a most common cause of mortality globally. Available medicines possess severe
side effects owing to their non-specific targeting. Hence, there is a need of an alternative in …

Distinct cytotoxic mechanisms of pristine versus hydroxylated fullerene

A Isakovic, Z Markovic… - Toxicological …, 2006 - academic.oup.com
The mechanisms underlying the cytotoxic action of pure fullerene suspension (nano-C60)
and water-soluble polyhydroxylated fullerene [C60 (OH) n] were investigated. Crystal violet …

In vivo oral insulin delivery via covalent organic frameworks

F Benyettou, N Kaddour, T Prakasam, G Das… - Chemical …, 2021 - pubs.rsc.org
With diabetes being the 7th leading cause of death worldwide, overcoming issues limiting
the oral administration of insulin is of global significance. The development of imine-linked …