Tracking placental development in health and disease

JD Aplin, JE Myers, K Timms… - Nature Reviews …, 2020 - nature.com
Pre-eclampsia and fetal growth restriction arise from disorders of placental development and
have some shared mechanistic features. Initiation is often rooted in the maldevelopment of a …

The placenta in fetal growth restriction: what is going wrong?

C Sun, KM Groom, C Oyston, LW Chamley, AR Clark… - Placenta, 2020 - Elsevier
The placenta is essential for the efficient delivery of nutrients and oxygen from mother to
fetus to maintain normal fetal growth. Dysfunctional placental development underpins many …

Combined diffusion‐relaxometry microstructure imaging: Current status and future prospects

PJ Slator, M Palombo, KL Miller… - Magnetic resonance …, 2021 - Wiley Online Library
Microstructure imaging seeks to noninvasively measure and map microscopic tissue
features by pairing mathematical modeling with tailored MRI protocols. This article reviews …

Unique microRNA signals in plasma exosomes from pregnancies complicated by preeclampsia

H Li, Y Ouyang, E Sadovsky, WT Parks, T Chu… - …, 2020 - Am Heart Assoc
Although preeclampsia is a common and serious complication of pregnancy, insight into its
pathobiology and diagnosis is lacking. Circulating plasma exosomes, which contain RNA …

Combined diffusion‐relaxometry MRI to identify dysfunction in the human placenta

PJ Slator, J Hutter, M Palombo… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose A combined diffusion‐relaxometry MR acquisition and analysis pipeline for in vivo
human placenta, which allows for exploration of coupling between and apparent diffusion …

T2* placental magnetic resonance imaging in preterm preeclampsia: an observational cohort study

AEP Ho, J Hutter, LH Jackson, PT Seed, L Mccabe… - …, 2020 - Am Heart Assoc
Placental dysfunction underlies the cause of pregnancies complicated by preeclampsia. The
use of placental magnetic resonance imaging to provide an insight into the pathophysiology …

[PDF][PDF] T2* weighted placental MRI: basic research tool or emerging clinical test for placental dysfunction?

A Sørensen, J Hutter, M Seed, PE Grant… - Ultrasound in Obstetrics …, 2020 - vbn.aau.dk
T2* weighted Placental MRI: Basic research tool or an emerging clinical test of placental
dysfunction? Page 1 Aalborg Universitet T2* weighted placental MRI basic research tool or …

Fetal growth restriction and stillbirth: Biomarkers for identifying at risk fetuses

VJ King, L Bennet, PR Stone, A Clark, AJ Gunn… - Frontiers in …, 2022 - frontiersin.org
Fetal growth restriction (FGR) is a major cause of stillbirth, prematurity and impaired
neurodevelopment. Its etiology is multifactorial, but many cases are related to impaired …

Placental MRI and its application to fetal intervention

R Aughwane, E Ingram, ED Johnstone… - Prenatal …, 2020 - Wiley Online Library
Objective Magnetic resonance imaging (MRI) of placental invasion has been part of clinical
practice for many years. The possibility of being better able to assess placental …

Hemodynamic responses of the placenta and brain to maternal hyperoxia in fetuses with congenital heart disease by using blood oxygen–level dependent MRI

W You, NN Andescavage, K Kapse, MT Donofrio… - Radiology, 2020 - pubs.rsna.org
Background Impaired brain development in fetuses with congenital heart disease (CHD)
may result from inadequate cerebral oxygen supply in utero. Purpose To test whether fetal …