Leukocyte migration is a crucial process in both homeostatic and inflammatory conditions.
The spatiotemporal distribution of immune cells is balanced between processes of cellular …

Leukocyte trafficking between blood and tissues is an essential function of the immune
system that facilitates humoral and cellular immune responses. Within tissues, leukocytes …

Objective Somatic mutations in UBA1 cause a newly defined syndrome known as VEXAS
(vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome). More than 50% of …

Clinical syndrome coronavirus disease 2019 (COVID-19) induced by severe acute
respiratory syndrome coronavirus 2 is characterized by rapid spreading and high mortality …

A large number of nanoparticles (NPs) have been raised for diverse biomedical applications
and some of them have shown great potential in treatment and imaging of diseases. Design …

Cells actively interact with their microenvironment, constantly sensing and modulating
biochemical and biophysical signals. Blood comprises a variety of non-adherent cells that …

While microscopy-based cellular assays, including microfluidics, have significantly
advanced over the last several decades, there has not been concurrent development of …

The quantification of blood cells provides critical information about a patient's health status.
Sophisticated analytical equipment, such as hematology analyzers, have been developed to …

Microengineering advances have enabled the development of perfusable, endothelialized
models of the microvasculature that recapitulate the unique biological and biophysical …

Abstract Microvasculatures-on-a-chip, ie in vitro models that mimic important features of
microvessel networks, have gained increasing interest in recent years. Such devices have …