Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

There is now overwhelming experimental and clinical evidence that atherosclerosis is a
chronic inflammatory disease. Lessons from genome-wide association studies, advanced in …

Multiple modes of cell death have been identified, each with a unique function and each
induced in a setting-dependent manner. As billions of cells die during mammalian …

The prompt removal of apoptotic cells by phagocytes is important for maintaining tissue
homeostasis. The molecular and cellular events that underpin apoptotic cell recognition and …

Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …

Atherosclerosis is a chronic inflammatory disorder that is the underlying cause of most
cardiovascular disease. Both cells of the vessel wall and cells of the immune system …

Inflammation contributes to many of the characteristics of plaques implicated in the
pathogenesis of acute coronary syndromes. Moreover, inflammatory pathways not only …

Nonclassical patrolling monocytes are characterized by their unique ability to actively patrol
the vascular endothelium under homeostatic and inflammatory conditions. Patrolling …

Leishmaniasis is a vector-borne neglected tropical disease that affects more than 700,000
people annually. Leishmania parasites cause the disease, and different species trigger a …