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[HTML][HTML] Major histocompatibility complex and peptide specificity underpin CD8+ T cell direct alloresponse
The direct alloresponse, pivotal in transplant rejection, occurs when recipient T cells
recognize intact allogeneic peptide-major histocompatibility complex (pMHC) complexes …
recognize intact allogeneic peptide-major histocompatibility complex (pMHC) complexes …
Clinical application of immune repertoire sequencing in solid organ transplant
Background Measurement of T cell receptor (TCR) or B cell receptor (BCR) gene utilization
may be valuable in monitoring the dynamic changes in donor-reactive clonal populations …
may be valuable in monitoring the dynamic changes in donor-reactive clonal populations …
Dissecting genetic control of HLA-DPB1 expression and its relation to structural mismatch models in hematopoietic stem cell transplantation
T Meurer, E Arrieta-Bolaños, M Metzing… - Frontiers in …, 2018 - frontiersin.org
HLA expression levels have been suggested to be genetically controlled by single
nucleotide polymorphisms (SNP) in the untranslated regions (UTR), and expression variants …
nucleotide polymorphisms (SNP) in the untranslated regions (UTR), and expression variants …
Comparative evaluation of biological human leukocyte antigen DPB1 mismatch models for survival and graft-versus-host disease prediction after unrelated donor …
Hematopoietic cell transplantation (HCT) from unrelated donors (UD) is a curative therapy
for many hematologic malignancies. Donor-recipient allele-level matching at human …
for many hematologic malignancies. Donor-recipient allele-level matching at human …
CD8+ T-cell repertoire in human leukocyte antigen class I-Mismatched alloreactive immune response
F Bettens, Z Calderin Sollet, S Buhler… - Frontiers in …, 2021 - frontiersin.org
In transplantation, direct allorecognition is a complex interplay between T-cell receptors
(TCR) and HLA molecules and their bound peptides expressed on antigen-presenting cells …
(TCR) and HLA molecules and their bound peptides expressed on antigen-presenting cells …
[HTML][HTML] TCR Sequencing in Mouse Models of Allorecognition Unveils the Features of Directly and Indirectly Activated Clonotypes
V Tereshchenko, D Shevyrev, M Fisher… - International Journal of …, 2023 - mdpi.com
Allorecognition is known to involve a large number of lymphocytes carrying diverse T-cell
receptor repertoire. Thus, one way to understand allorecognition and rejection mechanisms …
receptor repertoire. Thus, one way to understand allorecognition and rejection mechanisms …
Use of DPB1 T‐cell epitope algorithm among italian transplant centers: A survey on behalf of Associazione Italiana di Immunogenetica e Biologia dei Trapianti
R Crocchiolo, L Mele, M Testi, M Scollo Chiara… - HLA, 2021 - Wiley Online Library
The HLA‐DPB1 locus has been demonstrated to have a significant role on patients' outcome
after allogeneic HSCT, and the so‐called T‐cell epitope (TCE) algorithm has been …
after allogeneic HSCT, and the so‐called T‐cell epitope (TCE) algorithm has been …
[PDF][PDF] " Optimizing clinical outcome in allogeneic hematopoietic stem cell transplantation: pre-transplant and post-transplant immunogenetic markers
S BUHLER - access.archive-ouverte.unige.ch
Allogeneic hematopoietic stem cell transplantation (alloHSCT) is a standard treatment for
hematological disorders like acute leukemia and primary immune deficiencies. Various …
hematological disorders like acute leukemia and primary immune deficiencies. Various …
Learning the next-generation sequencing alphabet of immune reconstitution: factors determining CD8+ T-cell receptor α-chain repertoire dynamics after hematopoietic …
E Arrieta-Bolaños, K Fleischhauer - haematologica, 2019 - pmc.ncbi.nlm.nih.gov
E-mail: KATHARINA FLEISCHHAUER-katharina. fleischhauer@ uk-essen. de doi:
10.3324/haematol. 2018.209130 immune reconstitution after HLA-identical sibling HSCT in …
10.3324/haematol. 2018.209130 immune reconstitution after HLA-identical sibling HSCT in …
The Pursuit of Regulatory T Cells in the Induction of Transplant Tolerance
PR Arnold, XC Li - T Regulatory Cells in Human Health and Diseases, 2021 - Springer
Organ transplantation is a preferred treatment option for patients with end-stage organ
failure. However, transplant induces a robust rejection response that necessitates life-long …
failure. However, transplant induces a robust rejection response that necessitates life-long …