Current progress in expansion microscopy: chemical strategies and applications

G Wen, V Leen, T Rohand, M Sauer… - Chemical …, 2023 - ACS Publications
Expansion microscopy (ExM) is a newly developed super-resolution technique, allowing
visualization of biological targets at nanoscale resolution on conventional fluorescence …

Expansion microscopy: A chemical approach for super-resolution microscopy

Y Zhuang, X Shi - Current opinion in structural biology, 2023 - Elsevier
Super-resolution microscopy is a series of imaging techniques that bypass the diffraction
limit of resolution. Since the 1990s, optical approaches, such as single-molecular …

Semiconducting polymer nanoparticles with surface‐mimicking protein secondary structure as lysosome‐targeting chimaeras for self‐synergistic cancer …

J Qi, S Jia, X Kang, X Wu, Y Hong, K Shan… - Advanced …, 2022 - Wiley Online Library
Immunotherapy has received tremendous attention for tumor treatment, but the efficacy is
greatly hindered by insufficient tumor‐infiltration of immune cells and immunosuppressive …

An amplification-free digital assay based on primer exchange reaction-mediated botryoidal-like fluorescent polystyrene dots to detect multiple pathogenic bacteria

Z Wang, A Ma, Y Chen - ACS nano, 2024 - ACS Publications
Multiple and ultrasensitive detection of pathogenic bacteria is critical but remains a
challenge. Here, we introduce a digital assay for multiplexed and target DNA amplification …

Surface-engineered gold nanoclusters for stimulated emission depletion and correlated light and electron microscopy imaging

H Yang, Y Wu, H Ruan, F Guo, Y Liang, G Qin… - Analytical …, 2022 - ACS Publications
Stimulated emission depletion (STED) nanoscopy is an emerging super-resolution imaging
platform for the study of the cellular structure. Develo** suitable fluorescent probes of …

Expansion microscopy using a single anchor molecule for high-yield multiplexed imaging of proteins and RNAs

Y Cui, G Yang, DR Goodwin, CH O'Flanagan, A Sinha… - Plos one, 2023 - journals.plos.org
Expansion microscopy (ExM), by physically enlarging specimens in an isotropic fashion,
enables nanoimaging on standard light microscopes. Key to existing ExM protocols is the …

Expansion microscopy with ninefold swelling (NIFS) hydrogel permits cellular ultrastructure imaging on conventional microscope

H Li, AR Warden, J He, G Shen, X Ding - Science Advances, 2022 - science.org
Superresolution microscopy enables probing of cellular ultrastructures. However, its
widespread applications are limited by the need for expensive machinery, specific …

Anisotropic assembly and fluorescence enhancement of conjugated polymer nanostructures

X Men, X Fang, Z Liu, Z Zhang, C Wu, H Chen - View, 2022 - Wiley Online Library
The electronic properties of conjugated polymers depend sensitively on their conformation
and morphology. However, control over the morphology of conjugated polymers is highly …

A pH-responsive nanoplatform based on fluorescent conjugated polymer dots for imaging-guided multitherapeutics delivery and combination cancer therapy

Y Wang, X **ong, Y Zhu, X Song, Q Li… - … Biomaterials Science & …, 2021 - ACS Publications
For cancer treatment, nanocarriers were designed with cationic lipids and polymers to
improve the cytosolic delivery efficiency of siRNA. Though the positively charged …

Conjugated Polymeric Materials in Biological Imaging and Cancer Therapy

Q Zheng, Z Duan, Y Zhang, X Huang, X **ong, A Zhang… - Molecules, 2023 - mdpi.com
Conjugated polymers (CPs) have attracted much attention in the fields of chemistry,
medicine, life science, and material science. Researchers have carried out a series of …