Contributions of eosinophils to human health and disease
AD Klion, SJ Ackerman… - Annual Review of …, 2020 - annualreviews.org
The human eosinophil has long been thought to favorably influence innate mucosal
immunity but at times has also been incriminated in disease pathophysiology. Research into …
immunity but at times has also been incriminated in disease pathophysiology. Research into …
Eosinophil granule proteins: form and function
KR Acharya, SJ Ackerman - Journal of Biological Chemistry, 2014 - ASBMB
Experimental and clinical data strongly support a role for the eosinophil in the pathogenesis
of asthma, allergic and parasitic diseases, and hypereosinophilic syndromes, in addition to …
of asthma, allergic and parasitic diseases, and hypereosinophilic syndromes, in addition to …
British Society of Gastroenterology (BSG) and British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN) joint consensus guidelines on the …
Background Eosinophilic oesophagitis (EoE) is an increasingly common cause of dysphagia
in both children and adults, as well as one of the most prevalent oesophageal diseases with …
in both children and adults, as well as one of the most prevalent oesophageal diseases with …
Efficacy of dietary interventions for inducing histologic remission in patients with eosinophilic esophagitis: a systematic review and meta-analysis
Background & Aims Various dietary interventions have been used to treat patients with
eosinophilic esophagitis (EoE), yielding varied results. This systematic review assesses the …
eosinophilic esophagitis (EoE), yielding varied results. This systematic review assesses the …
Diagnosis and treatment of eosinophilic esophagitis
NP Gonsalves, SS Aceves - Journal of Allergy and Clinical Immunology, 2020 - Elsevier
Eosinophilic esophagitis (EoE) is an eosinophil-rich, TH 2 antigen–mediated disease of
increasing pediatric and adult worldwide prevalence. Diagnosis requires greater than or …
increasing pediatric and adult worldwide prevalence. Diagnosis requires greater than or …
Symptoms have modest accuracy in detecting endoscopic and histologic remission in adults with eosinophilic esophagitis
Background & Aims It is not clear whether symptoms alone can be used to estimate the
biologic activity of eosinophilic esophagitis (EoE). We aimed to evaluate whether symptoms …
biologic activity of eosinophilic esophagitis (EoE). We aimed to evaluate whether symptoms …
Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis
Background Eosinophilic esophagitis (EoE) is a chronic antigen-driven allergic inflammatory
disease, likely involving the interplay of genetic and environmental factors, yet their …
disease, likely involving the interplay of genetic and environmental factors, yet their …
Endoscopic approach to eosinophilic esophagitis: American Society for Gastrointestinal Endoscopy consensus conference
SS Aceves, JA Alexander, TH Baron… - Gastrointestinal …, 2022 - Elsevier
Endoscopy plays a critical role in caring for and evaluating the patient with eosinophilic
esophagitis (EoE). Endoscopy is essential for diagnosis, assessment of response to therapy …
esophagitis (EoE). Endoscopy is essential for diagnosis, assessment of response to therapy …
Management guidelines of eosinophilic esophagitis in childhood
A Papadopoulou, S Koletzko… - Journal of pediatric …, 2014 - journals.lww.com
Objectives: Eosinophilic esophagitis (EoE) represents a chronic, immune/antigen-mediated
esophageal disease characterized clinically by symptoms related to esophageal dysfunction …
esophageal disease characterized clinically by symptoms related to esophageal dysfunction …
The microbiome and food allergy
The gut-associated lymphoid tissue (GALT) faces a considerable challenge. It encounters
antigens derived from an estimated 1014 commensal microbes and greater than 30 kg of …
antigens derived from an estimated 1014 commensal microbes and greater than 30 kg of …