The epithelial–mesenchymal transition (EMT) is a developmental program that enables
stationary epithelial cells to gain the ability to migrate and invade as single cells. Tumor cells …

Tumor metastasis is a multistep process by which tumor cells disseminate from their primary
site and form secondary tumors at a distant site. Metastasis occurs through a series of steps …

Matrix stiffness potently regulates cellular behaviour in various biological contexts. In breast
tumours, the presence of dense clusters of collagen fibrils indicates increased matrix …

Epithelial–mesenchymal transition (EMT) has been implicated in various aspects of tumor
development, including tumor invasion and metastasis, cancer stemness, and therapy …

Tumor metastasis is a multi-step process by which tumor cells disseminate from their primary
site and form secondary tumors at a distant site. And metastasis is the major cause of death …

Cancer is a complex multistep process involving genetic and epigenetic changes that
eventually result in the activation of oncogenic pathways and/or inactivation of tumor …

The epithelial to mesenchymal transition (EMT) converts epithelial cells into migratory and
invasive cells and is a fundamental event in morphogenesis. Although its relevance in the …

CD44, a multi-structural and multifunctional transmembrane glycoprotein, was initially
identified as a receptor for hyaluronan that participates in both physiological and …

Background & Aims Acute pancreatitis (AP) is a complex disease and the leading cause of
gastrointestinal disease–related hospital admissions. Few therapeutic options exist for AP …

The origins of the complex process of intratumoral heterogeneity have been highly debated
and different cellular mechanisms have been hypothesized to account for the diversity within …