The zoonotic potential of chronic wasting disease—a review

MA Tranulis, M Tryland - Foods, 2023 - mdpi.com
Prion diseases are transmissible neurodegenerative disorders that affect humans and
ruminant species consumed by humans. Ruminant prion diseases include bovine …

Update on classical and atypical scrapie in sheep and goats

JJ Greenlee - Veterinary pathology, 2019 - journals.sagepub.com
Scrapie is a naturally occurring transmissible spongiform encephalopathy (TSE) or prion
disease of sheep and goats. Scrapie is a protein misfolding disease where the normal prion …

Neuropathology of animal prion diseases

L Orge, C Lima, C Machado, P Tavares, P Mendonça… - Biomolecules, 2021 - mdpi.com
Transmissible Spongiform Encephalopathies (TSEs) or prion diseases are a fatal group of
infectious, inherited and spontaneous neurodegenerative diseases affecting human and …

Isolation of prion with BSE properties from farmed goat

J Spiropoulos, R Lockey, RE Sallis… - Emerging infectious …, 2011 - pmc.ncbi.nlm.nih.gov
Transmissible spongiform encephalopathies are fatal neurodegenerative diseases that
include variant Creutzfeldt-Jakob disease in humans, scrapie in small ruminants, and bovine …

The gut-associated lymphoid tissues in the small intestine, not the large intestine, play a major role in oral prion disease pathogenesis

DS Donaldson, KJ Else, NA Mabbott - Journal of virology, 2015 - journals.asm.org
Prion diseases are infectious neurodegenerative disorders characterized by accumulations
of abnormally folded cellular prion protein in affected tissues. Many natural prion diseases …

The transmissible spongiform encephalopathies of livestock

JJ Greenlee, MHW Greenlee - ILAR journal, 2015 - academic.oup.com
Prion diseases or transmissible spongiform encephalopathies (TSEs) are fatal protein-
misfolding neurodegenerative diseases. TSEs have been described in several species …

Prion protein polymorphisms associated with reduced CWD susceptibility limit peripheral PrPCWD deposition in orally infected white-tailed deer

A Otero, C Duque Velásquez, C Johnson… - BMC veterinary …, 2019 - Springer
Background Chronic wasting disease (CWD) is a prion disease affecting members of the
Cervidae family. PrP C primary structures play a key role in CWD susceptibility resulting in …

Neuroinvasion in prion diseases: the roles of ascending neural infection and blood dissemination

S Sisó, L González, M Jeffrey - Interdisciplinary perspectives on …, 2010 - Wiley Online Library
Prion disorders are infectious, neurodegenerative diseases that affect humans and animals.
Susceptibility to some prion diseases such as kuru or the new variant of Creutzfeldt‐Jakob …

[HTML][HTML] How do PrPSc Prions Spread between Host Species, and within Hosts?

NA Mabbott - Pathogens, 2017 - mdpi.com
Prion diseases are sub-acute neurodegenerative diseases that affect humans and some
domestic and free-ranging animals. Infectious prion agents are considered to comprise …

Caprine prion gene polymorphisms are associated with decreased incidence of classical scrapie in goat herds in the United Kingdom

W Goldmann, K Ryan, P Stewart, D Parnham… - Veterinary …, 2011 - Springer
The application of genetic breeding programmes to eradicate transmissible spongiform
encephalopathies in goats is an important aim for reasons of animal welfare as well as …