Cancer, a complex and multifactorial disease, presents a significant challenge to global
health. Despite significant advances in surgical, radiotherapeutic and immunological …

T cells are crucial for immune functions to maintain health and prevent disease. T cell
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …

RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

The innate immune pathway is receiving increasing attention in cancer therapy. This
pathway is ubiquitous across various cell types, not only in innate immune cells but also in …

T helper (Th) cells have received extensive attention owing to their indispensable roles in
anti-tumor immune responses. Th1 and Th2 cells are two key subsets of Th cells that exist in …

Personalized tumor vaccines have become a promising modality for cancer immunotherapy.
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …

Current success of immunotherapy in cancer has drawn attention to the subsets of TH cells
in the tumor which are critical for activation of anti-tumor response either directly by …

Metabolic dysfunction-associated steatotic liver disease (MASLD) is an unabated risk factor
for end-stage liver diseases with no available therapies. Dysregulated immune responses …

Abstract α-Synuclein, a key pathological component of Parkinson's disease, has been
implicated in the activation of the innate and adaptive immune system. This immune …

T cells are an important component of adaptive immunity and protect the host from infectious
diseases and cancers. However, uncontrolled T cell immunity may cause autoimmune …