Immune cell interactions in tuberculosis
JAL Flynn, J Chan - Cell, 2022 - cell.com
Despite having been identified as the organism that causes tuberculosis in 1882,
Mycobacterium tuberculosis has managed to still evade our understanding of the protective …
Mycobacterium tuberculosis has managed to still evade our understanding of the protective …
New insights into the evasion of host innate immunity by Mycobacterium tuberculosis
Q Chai, L Wang, CH Liu, B Ge - Cellular & molecular immunology, 2020 - nature.com
Mycobacterium tuberculosis (Mtb) is an extremely successful intracellular pathogen that
causes tuberculosis (TB), which remains the leading infectious cause of human death. The …
causes tuberculosis (TB), which remains the leading infectious cause of human death. The …
Differential diagnosis of latent tuberculosis infection and active tuberculosis: a key to a successful tuberculosis control strategy
W Gong, X Wu - Frontiers in microbiology, 2021 - frontiersin.org
As an ancient infectious disease, tuberculosis (TB) is still the leading cause of death from a
single infectious agent worldwide. Latent TB infection (LTBI) has been recognized as the …
single infectious agent worldwide. Latent TB infection (LTBI) has been recognized as the …
The relationship between nutrition and the immune system
C Munteanu, B Schwartz - Frontiers in nutrition, 2022 - frontiersin.org
Nutrition plays an essential role in the regulation of optimal immunological response, by
providing adequate nutrients in sufficient concentrations to immune cells. There are a large …
providing adequate nutrients in sufficient concentrations to immune cells. There are a large …
Clinical utility of in-house metagenomic next-generation sequencing for the diagnosis of lower respiratory tract infections and analysis of the host immune response
Background Only few pathogens that cause lower respiratory tract infections (LRTIs) can be
identified due to limitations of traditional microbiological methods and the complexity of the …
identified due to limitations of traditional microbiological methods and the complexity of the …
Dynamic balance of pro‐and anti‐inflammatory signals controls disease and limits pathology
Immune responses to pathogens are complex and not well understood in many diseases,
and this is especially true for infections by persistent pathogens. One mechanism that allows …
and this is especially true for infections by persistent pathogens. One mechanism that allows …
Harnessing the beneficial heterologous effects of vaccination
HS Goodridge, SS Ahmed, N Curtis… - Nature Reviews …, 2016 - nature.com
Clinical evidence strongly suggests that certain live vaccines, in particular bacille Calmette–
Guérin (BCG) and measles vaccines, can reduce all-cause mortality, most probably through …
Guérin (BCG) and measles vaccines, can reduce all-cause mortality, most probably through …
Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease
Our understanding of mechanisms underlying progression from Mycobacterium tuberculosis
infection to pulmonary tuberculosis disease in humans remains limited. To define such …
infection to pulmonary tuberculosis disease in humans remains limited. To define such …
Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung
T cell immunity is essential for the control of tuberculosis (TB), an important disease of the
lung, and is generally studied in humans using peripheral blood cells. Mounting evidence …
lung, and is generally studied in humans using peripheral blood cells. Mounting evidence …
In the thick of it: formation of the tuberculous granuloma and its effects on host and therapeutic responses
MR Cronan - Frontiers in immunology, 2022 - frontiersin.org
The defining pathology of tuberculosis is the granuloma, an organized structure derived from
host immune cells that surrounds infecting Mycobacterium tuberculosis. As the location of …
host immune cells that surrounds infecting Mycobacterium tuberculosis. As the location of …