Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …

The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

Nucleoside analogues have been in clinical use for almost 50 years and have become
cornerstones of treatment for patients with cancer or viral infections. The approval of several …

In the recent years, protein PEGylation has become an established and highly refined
technology by moving forward from initial simple random coupling approaches based on …

Liposomes are very useful biocompatible tools used in diverse scientific disciplines,
employed for the vehiculation and delivery of lipophilic, ampiphilic or hydrophilic …

Gemcitabine is an antimetabolite ranking among the most prescribed anticancer drugs
worldwide. This nucleoside analog exerts its antiproliferative action after tumoral conversion …

Poly (ethylene glycol)(PEG) is the most widely used polymer in delivering anticancer drugs
clinically. PEGylation (ie, the covalent attachment of PEG) of peptides proteins, drugs, and …

Since the early days marking the first use of nanomedicine in the early 80s, there has been a
meaningful change in the scientific field involving the Fabrication, characterization, and …

Shortage of functional groups on surface of poly (lactide-co-glycolide)(PLGA)-based drug
delivery carriers always hampers its wide applications such as passive targeting and …

During the almost forty years of PEGylation, several antitumour agents, either proteins,
peptides or low molecular weight drugs, have been considered for polymer conjugation but …