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The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …
physiological and pathological events in biology. Metal coordination chemistry, especially …
Carbonyl stress in red blood cells and hemoglobin
OV Kosmachevskaya, NN Novikova, AF Topunov - Antioxidants, 2021 - mdpi.com
The paper overviews the peculiarities of carbonyl stress in nucleus-free mammal red blood
cells (RBCs). Some functional features of RBCs make them exceptionally susceptible to …
cells (RBCs). Some functional features of RBCs make them exceptionally susceptible to …
[HTML][HTML] Histidine-Bound Dinitrosyl Iron Complexes: Antioxidant and Antiradical Properties
KB Shumaev, OV Kosmachevskaya… - International Journal of …, 2023 - mdpi.com
Dinitrosyl iron complexes (DNICs) are important physiological derivatives of nitric oxide.
These complexes have a wide range of biological activities, with antioxidant and antiradical …
These complexes have a wide range of biological activities, with antioxidant and antiradical …
The effect of hypochlorous acid inhalation on the activity of antioxidant system enzymes in rats of different ages
Hypochlorous acid HOCl is an effective disinfectant with a broad spectrum and high rate of
microbicidal action. Its use for air treatment can be an effective tool for the prevention and …
microbicidal action. Its use for air treatment can be an effective tool for the prevention and …
Protective effect of dinitrosyl iron complexes bound with hemoglobin on oxidative modification by peroxynitrite
OV Kosmachevskaya, EI Nasybullina… - International Journal of …, 2021 - mdpi.com
Dinitrosyl iron complexes (DNICs) are a physiological form of nitric oxide (• NO) in an
organism. They are able not only to deposit and transport• NO, but are also to act as …
organism. They are able not only to deposit and transport• NO, but are also to act as …
Effects of Nitrosyl Iron Complexes with Thiol, Phosphate, and Thiosulfate Ligands on Hemoglobin
OV Kosmachevskaya, EI Nasybullina… - International Journal of …, 2024 - mdpi.com
Nitrosyl iron complexes are remarkably multifactorial pharmacological agents. These
compounds have been proven to be particularly effective in treating cardiovascular and …
compounds have been proven to be particularly effective in treating cardiovascular and …
Effect of iron–nitric oxide complexes on the reactivity of hemoglobin cysteines
OV Kosmachevskaya, EI Nasybullina… - Applied Biochemistry …, 2020 - Springer
Human erythrocyte hemoglobin (Hb) has two reactive cysteines located on the surface of β-
subunits. These cysteines play an important role in the adjustment of Hb functions. It is …
subunits. These cysteines play an important role in the adjustment of Hb functions. It is …
Formation of Supplementary Metal-Binding Centers in Proteins under Stress Conditions
OV Kosmachevskaya, NN Novikova, SN Yakunin… - Biochemistry …, 2024 - Springer
In many proteins, supplementary metal-binding centers appear under stress conditions.
They are known as aberrant or atypical sites. Physico-chemical properties of proteins are …
They are known as aberrant or atypical sites. Physico-chemical properties of proteins are …
Effects of glutathione and histidine on NO release from a dimeric dinitrosyl iron complex (DNIC)
Rates of NO release from synthetic dinitrosyl iron complexes (DNICs) are shown to be
responsive to coordination environments about iron. The effect of biologically relevant …
responsive to coordination environments about iron. The effect of biologically relevant …
The Effect of Peroxynitrite and tert-Butyl Hydroperoxide on Thiol Ligands of Dinitrosyl Iron Complexes
IS Pugachenko, EI Nasybullina… - Applied Biochemistry …, 2023 - Springer
Low-molecular-weight dinitrosyl iron complexes (DNICs) with thiol-containing ligands are a
physiological form for deposit and transport of nitric oxide (NO) in the organism; DNICs can …
physiological form for deposit and transport of nitric oxide (NO) in the organism; DNICs can …