Antiepileptic drugs in aquatic environments: Occurrence, toxicity, transformation mechanisms and fate

Q Liu, L Wang, X Xu, S Yan, J Zha… - Critical Reviews in …, 2023 - Taylor & Francis
The increasing consumption of antiepileptic drugs (AEDs) has led to their widespread
presence in aquatic environments, which poses a serious threat to human health and …

Psychotropic drugs of emerging concerns in aquatic systems: ecotoxicology and remediation approaches

AO Adeola, OT Ore, O Fapohunda, AH Adewole… - Chemistry Africa, 2022 - Springer
Carbamazepine (CBZ) and diazepam (DZP) are often prescribed for the treatment of stress,
muscle spasm, anxiety, alcohol withdrawal symptoms, convulsion, and epileptic conditions …

Zeolitic imidazolate frameworks as effective crystalline supports for aspergillus-based laccase immobilization for the biocatalytic degradation of carbamazepine

ML Dlamini, M Lesaoana, I Kotze, HL Richards - Chemosphere, 2023 - Elsevier
In this study, zeolitic imidazolate frameworks (ZIF) were employed as effective porous
supports for laccase enzyme attachment and further explored synergistic adsorption and …

Ajugol enhances TFEB-mediated lysosome biogenesis and lipophagy to alleviate non-alcoholic fatty liver disease

H Zhang, J Lu, H Liu, L Guan, S Xu, Z Wang… - Pharmacological …, 2021 - Elsevier
Lipophagy is the autophagic degradation of lipid droplets. Dysregulated lipophagy has been
implicated in the development of non-alcoholic fatty liver disease (NAFLD). Ajugol is an …

Carbamazepine at environmentally relevant concentrations caused DNA damage and apoptosis in the liver of Chinese rare minnows (Gobiocypris rarus) by the Ras …

S Yan, R Chen, M Wang, J Zha - Environmental Pollution, 2021 - Elsevier
To assess genetoxicity and the underlying mechanisms of carbamazepine (CBZ) toxicity in
fish, adult Chinese rare minnows (Gobiocypris rarus) were exposed to 1, 10, and 100 μg/L …

Carbamazepine induces hepatotoxicity in zebrafish by inhibition of the Wnt/β-catenin signaling pathway

Z Bai, K Jia, G Chen, X Liao, Z Cao, Y Zhao… - Environmental …, 2021 - Elsevier
As drug abuse has become increasingly serious, carbamazepine (CBZ) is discharged into
the aquatic environment with municipal sewage, causing potential harm to aquatic …

Comparison of the toxicity effects of tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP) with tributyl phosphate (TNBP) reveals the mechanism of the apoptosis pathway …

S Yan, Q Wang, L Yang, J Zha - Environmental Science & …, 2020 - ACS Publications
To compare the toxicities of a chlorinated and a nonchlorinated organophosphorus flame
retardant (OPFR) in this study, adult calms (Corbicula fluminea) were exposed to tris (1, 3 …

Combination of herbal extracts regulates growth performance, liver and intestinal morphology, antioxidant capacity, and intestinal microbiota in Acrossocheilus …

YT Shen, ZL Ding, XY Wang, WQ Chen, RX **a… - Aquaculture, 2025 - Elsevier
In the present study, the herbal extracts (RPTS) composed of Rheum palmatum: Schisandra
sphenanthera: Terminalia chebula: Punica granatum with a weight ratio of 1.07: 3.00: 1.18 …

[HTML][HTML] Macrophage targeted graphene oxide nanosystem synergize antibiotic killing and host immune defense for Tuberculosis Therapy

J Pi, D Chen, J Wang, E Yang, J Yang, Y Liu… - Pharmacological …, 2024 - Elsevier
Tuberculosis (TB), a deadly disease caused by Mycobacterium tuberculosis (Mtb) infection,
remains one of the top killers among infectious diseases worldwide. How to increase …

Effects of carbamazepine in aquatic biota

H Baali, C Cosio - Environmental Science: Processes & Impacts, 2022 - pubs.rsc.org
Carbamazepine (CBZ) is one of the most common pharmaceuticals found in the aquatic
environment. Here, we reviewed studies in aquatic animals highlighting that CBZ affected …