The immune microenvironment in gastric adenocarcinoma

Y Zavros, JL Merchant - Nature Reviews Gastroenterology & …, 2022 - nature.com
Like most solid tumours, the microenvironment of epithelial-derived gastric adenocarcinoma
(GAC) consists of a variety of stromal cell types, including fibroblasts, and neuronal …

The interplay between Helicobacter pylori and gastrointestinal microbiota

CC Chen, JM Liou, YC Lee, TC Hong, EM El-Omar… - Gut …, 2021 - Taylor & Francis
The complex population of microbes in the human gastrointestinal (GI) tract interacts with
itself and with the host, exerting a deep influence on health and disease development. The …

The Spectrum of Helicobacter-Mediated Diseases

K Robinson, JC Atherton - Annual Review of Pathology …, 2021 - annualreviews.org
Helicobacter pylori is the leading cause of peptic ulcer disease. The infection has been
implicated in more than 75% of duodenal ulcer cases and 17% of gastric ulcer cases. H …

The stomach in health and disease

RH Hunt, M Camilleri, SE Crowe, EM El-Omar, JG Fox… - Gut, 2015 - gut.bmj.com
The stomach is traditionally regarded as a hollow muscular sac that initiates the second
phase of digestion. Yet this simple view ignores the fact that it is the most sophisticated …

[HTML][HTML] Helicobacter pylori in human health and disease: Mechanisms for local gastric and systemic effects

D Bravo, A Hoare, C Soto, MA Valenzuela… - World journal of …, 2018 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is present in roughly 50% of the human population worldwide
and infection levels reach over 70% in develo** countries. The infection has classically …

Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori

NR Salama, ML Hartung, A Müller - Nature Reviews Microbiology, 2013 - nature.com
The bacterial pathogen Helicobacter pylori has co-evolved with humans and colonizes
approximately 50% of the human population, but only causes overt gastric disease in a …

Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

LE Wroblewski, RM Peek Jr… - Clinical microbiology …, 2010 - Am Soc Microbiol
Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

[HTML][HTML] Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium

DE Stange, BK Koo, M Huch, G Sibbel, O Basak… - Cell, 2013 - cell.com
Proliferation of the self-renewing epithelium of the gastric corpus occurs almost exclusively
in the isthmus of the glands, from where cells migrate bidirectionally toward pit and base …

TH17 cells in tumour immunity and immunotherapy

W Zou, NP Restifo - Nature Reviews Immunology, 2010 - nature.com
Abstract T helper 17 (TH17) cells have well-described roles in autoimmune disease. Recent
evidence suggests that this effector T cell subset is also involved in tumour immunology and …

Peptide-based vaccines for tuberculosis

W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …