Human pathologies such as vascular malformations, hemorrhagic stroke, and edema have
been associated with defects in the organization of endothelial cell junctions. Understanding …

cAMP is a second messenger that is essential for relaying hormonal responses in many
biological processes. The discovery of the cAMP target Epac explained various effects of …

Capillary malformation (CM), or" port-wine stain," is a common cutaneous vascular anomaly
that initially appears as a red macular stain that darkens over years. CM also occurs in …

Cerebral cavernous malformations (CCMs) are hamartomatous vascular malformations
characterized by abnormally enlarged capillary cavities without intervening brain …

Endothelial cell–cell junctions regulate vascular permeability, vasculogenesis, and
angiogenesis. Familial cerebral cavernous malformations (CCMs) in humans result from …

Cavernous angiomas are vascular malformations mostly located in the central nervous
system and characterized by enlarged capillary cavities without intervening brain …

Cerebral cavernous malformations (CCM) are vascular malformations that can occur as a
sporadic or a familial autosomal dominant disorder. Clinical and cerebral MRI data on large …

Cerebral cavernous malformations (CCM) are congenital vascular anomalies of the brain
that can cause significant neurological disabilities, including intractable seizures and …

Cerebral cavernous malformations (CCMs) are congenital vascular anomalies of the central
nervous system that can result in hemorrhagic stroke, seizures, recurrent headaches, and …

Cerebral cavernous malformation (CCM), a disease associated with defective endothelial
junctions, result from autosomal dominant CCM1 mutations that cause loss of KRIT-1 protein …