The ascarids are a large group of parasitic nematodes that infect a wide range of animal
species. In humans, they cause neglected diseases of poverty; many animal parasites also …

ABC transporters, a family of ATP-dependent transmembrane proteins, are responsible for
the active transport of a wide range of molecules across cell membranes, including drugs …

P-glycoproteins (Pgp) have been proposed as contributors to the widespread macrocyclic
lactone (ML) resistance in several nematode species including a major pathogen of foals …

The equine ascarids, Parascaris spp., are important nematode parasites of juvenile horses
and were historically model organisms in the field of cell biology, leading to many important …

Macrocyclic lactones (MLs) are widely used drugs to treat and prevent parasitic nematode
infections. In many nematode species including a major pathogen of foals, Parascaris …

P-glycoproteins from the ATP-binding cassette transporter family are responsible for drug
evasion by bacterial pathogens and neoplastic cells. More recently, these multidrug …

Haemonchus contortus, a blood-feeding nematode, inhibits blood coagulation at the site of
infection to facilitate blood-sucking and digesting for successful parasitism. However, the …

The nematode parasite intestine absorbs nutrients, is involved in innate immunity, can
metabolize xenobiotics and as we show here, is also a site of action of the anthelmintic …

Ascarid parasites infect a variety of hosts and regular anthelmintic treatment is
recommended for all species. Parascaris spp. is the only ascarid species with widespread …

First published in 1963, Advances in Parasitology contains comprehensive and up-to-date
reviews in all areas of interest in contemporary parasitology. Advances in Parasitology …