[HTML][HTML] Pathogenesis of chronic obstructive pulmonary disease (COPD) induced by cigarette smoke

M Hikichi, K Mizumura, S Maruoka… - Journal of thoracic …, 2019 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) is a common respiratory disease that is
characterized by functional and structural alterations primarily caused by long-term …

The role of immune cells in post-stroke angiogenesis and neuronal remodeling: the known and the unknown

Y Ma, S Yang, Q He, D Zhang, J Chang - Frontiers in immunology, 2021 - frontiersin.org
Following a cerebral ischemic event, substantial alterations in both cellular and molecular
activities occur due to ischemia-induced cerebral pathology. Mounting evidence indicates …

The dual role of neutrophils in inflammatory bowel diseases

O Wéra, P Lancellotti, C Oury - Journal of clinical medicine, 2016 - mdpi.com
Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are
characterised by aberrant immunological responses leading to chronic inflammation without …

Oxidative stress in COPD: sources, markers, and potential mechanisms

AJA McGuinness, E Sapey - Journal of clinical medicine, 2017 - mdpi.com
Markers of oxidative stress are increased in chronic obstructive pulmonary disease (COPD)
and reactive oxygen species (ROS) are able to alter biological molecules, signaling …

Prospects for COPD treatment

MG Matera, M Cazzola, C Page - Current Opinion in Pharmacology, 2021 - Elsevier
The management of chronic obstructive pulmonary disease (COPD) is fundamentally still
heavily dependent on the use of bronchodilators and corticosteroids. Therefore, there is a …

Novel anti-inflammatory approaches to COPD

M Cazzola, NA Hanania, CP Page… - International journal of …, 2023 - Taylor & Francis
Airway inflammation, driven by different types of inflammatory cells and mediators, plays a
fundamental role in COPD and its progression. Neutrophils, eosinophils, macrophages, and …

Glucocorticoids, their uses, sexual dimorphisms, and diseases: new concepts, mechanisms, and discoveries

GJ Martinez, M Appleton, ZA Kipp… - Physiological …, 2024 - journals.physiology.org
The normal stress response in humans is governed by the hypothalamic-pituitary-adrenal
(HPA) axis through heightened mechanisms during stress, raising blood levels of the …

Our evolving view of neutrophils in defining the pathology of chronic lung disease

KT Mincham, N Bruno, A Singanayagam… - …, 2021 - Wiley Online Library
Neutrophils are critical components of the body's immune response to infection, being
loaded with a potent arsenal of toxic mediators and displaying immense destructive …

Advanced role of neutrophils in common respiratory diseases

J Liu, Z Pang, G Wang, X Guan, K Fang… - Journal of …, 2017 - Wiley Online Library
Respiratory diseases, always being a threat towards the health of people all over the world,
are most tightly associated with immune system. Neutrophils serve as an important …

[HTML][HTML] ING5 knockdown enhances migration and invasion of lung cancer cells by inducing EMT via EGFR/PI3K/Akt and IL-6/STAT3 signaling pathways

XL Liu, XT Zhang, J Meng, HF Zhang, Y Zhao, C Li… - Oncotarget, 2017 - ncbi.nlm.nih.gov
ING5 belongs to the Inhibitor of Growth (ING) candidate tumor suppressor family, whose
functions have been involved in the regulation of chromatin remodeling, cell cycle …