The ability to detect disease early and deliver precision therapy would be transformative for
the treatment of human illnesses. To achieve these goals, biosensors that can pinpoint when …

Bacteria are single-celled organisms that carry a comparatively small set of genetic
information, typically consisting of a few thousand genes that can be selectively activated or …

The cold chain is an integral part of the modern food industry. Low temperatures can
effectively alleviate food loss and the transmission of foodborne diseases caused by …

The two-component system DesK-DesR regulates the synthesis of unsaturated fatty acids in
the soil bacteria Bacillus subtilis. This system is activated at low temperature and maintains …

DesK is a Histidine Kinase that allows Bacillus subtilis to maintain lipid homeostasis in
response to changes in the environment. It is located in the membrane, and has five …

Histidine Kinases (HK) modulate key cellular functions by phosphorylating specific proteins,
and thereby altering their activity or localization. Upon signal detection, HKs undergo …

While enzymes can be studied from the viewpoint of (a) the active site environment,(b) the
kinetic mechanism, and (c) the chemical mechanism, an enzyme is a unit and all these …

DesK is a Histidine Kinase that allows Bacillus subtilis to maintain lipid homeostasis in
response to changes in the environment. It is located in the membrane, and has five …