Biglycan is a member of the small leucine‐rich proteoglycan family. Dysregulation of
biglycan leads to a broad range of clinical consequences, such as osteoclastogenesis …

Biglycan, a pericellular small leucine-rich proteoglycan, is crucial in skeletal development
and regeneration. Intervertebral disc degeneration (IDD) contributes to back pain and …

Background Human induced pluripotent stem cells represent a scalable source of youthful
tissue progenitors and secretomes for regenerative therapies. The aim of our study was to …

Based on anti-inflammatory and osteogenic properties of hesperidin (HE), we hypothesized
its systemic administration could be a cost-effective method of improving BMP-induced bone …

Non-union fractures pose a significant clinical challenge, often leading to prolonged pain
and disability. Understanding the molecular mechanisms underlying non-union fractures is …

The Wnt signaling pathway is crucial for tooth development, odontoblast differentiation, and
dentin formation. It interacts with epithelial cadherin (E-cadherin) and beta-catenin in tooth …

Fracture healing is a complex process that involves multiple molecular events, and the
regulation mechanism is not fully understood. We acquired miRNA and mRNA …

Background Cartilage, characterized by its limited self-repair capacity due to avascularity
and low metabolic activity of chondrocytes, poses a significant challenge for regenerative …

Methods Based on multiple public databases, we investigated the expression level of BGN
in ccRCC, its clinical significance, and its association with immune cells. Real-time …