Circulating endocannabinoids: from whence do they come and where are they going?

CJ Hillard - Neuropsychopharmacology, 2018 - nature.com
The goal of this review is to summarize studies in which concentrations of circulating
endocannabinoids in humans have been examined in relationship to physiological …

Diverse therapeutic developments for post-traumatic stress disorder (PTSD) indicate common mechanisms of memory modulation

SB Raut, PA Marathe, L van Eijk, R Eri… - Pharmacology & …, 2022 - Elsevier
Post-traumatic stress disorder (PTSD), characterized by abnormally persistent and
distressing memories, is a chronic debilitating condition in need of new treatment options …

Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training

M Morena, B Roozendaal, V Trezza, P Ratano… - Proceedings of the …, 2014 - pnas.org
Previous studies have provided extensive evidence that administration of cannabinoid drugs
after training modulates the consolidation of memory for an aversive experience. The …

The basic science of cannabinoids

A Sideris, J Lauzadis, M Kaczocha - Anesthesia & Analgesia, 2024 - journals.lww.com
The cannabis plant has been used for centuries to manage the symptoms of various
ailments including pain. Hundreds of chemical compounds have been identified and …

Effect of dexmedetomidine on posttraumatic stress disorder in patients undergoing emergency trauma surgery: a randomized clinical trial

Y Yu, Y Li, D Han, C Gong, L Wang, B Li… - JAMA Network …, 2023 - jamanetwork.com
Importance Posttraumatic stress disorder (PTSD) is common in people who have
experienced trauma, especially those hospitalized for surgery. Dexmedetomidine may …

Enhancing endocannabinoid neurotransmission augments the efficacy of extinction training and ameliorates traumatic stress-induced behavioral alterations in rats

M Morena, A Berardi, P Colucci, M Palmery… - …, 2018 - nature.com
Exposure to a traumatic event may result in the development of post-traumatic stress
disorder (PTSD). Endocannabinoids are crucial modulators of the stress response, interfere …

On making (and turning adaptive to) maladaptive aversive memories in laboratory rodents

L Gazarini, CAJ Stern, LJ Bertoglio - Neuroscience & Biobehavioral …, 2023 - Elsevier
Fear conditioning and avoidance tasks usually elicit adaptive aversive memories. Traumatic
memories are more intense, generalized, inflexible, and resistant to attenuation via …