Delayed graft function in kidney transplant: risk factors, consequences and prevention strategies

C Ponticelli, F Reggiani, G Moroni - Journal of personalized medicine, 2022 - mdpi.com
Background. Delayed graft function is a frequent complication of kidney transplantation that
requires dialysis in the first week posttransplant. Materials and Methods. We searched for …

2024 AHA/ACC/ACS/ASNC/HRS/SCA/SCCT/SCMR/SVM guideline for perioperative cardiovascular management for noncardiac surgery: a report of the American …

Writing Committee Members, A Thompson… - Journal of the American …, 2024 - jacc.org
Abstract Aim The “2024 aha/acc/acs/asnc/hrs/sca/scct/scmr/svm Guideline for Perioperative
Cardiovascular Management for Noncardiac Surgery” provides recommendations to guide …

Implantable bioelectronic systems for early detection of kidney transplant rejection

SR Madhvapathy, JJ Wang, H Wang, M Patel, A Chang… - Science, 2023 - science.org
Early-stage organ transplant rejection can be difficult to detect. Percutaneous biopsies occur
infrequently and are risky, and measuring biomarker levels in blood can lead to false …

[HTML][HTML] MiR-20a-5p alleviates kidney ischemia/reperfusion injury by targeting ACSL4-dependent ferroptosis

L Shi, Z Song, Y Li, J Huang, F Zhao, Y Luo… - American Journal of …, 2023 - Elsevier
Ischemia/reperfusion injury (IRI) is prone to occur after kidney transplantation, leading to
delayed graft function (DGF). MicroRNAs play a crucial role in the pathogenesis of …

Gut microbiome modulates tacrolimus pharmacokinetics through the transcriptional regulation of ABCB1

AL Degraeve, V Haufroid, A Loriot, L Gatto, V Andries… - Microbiome, 2023 - Springer
Background Following solid organ transplantation, tacrolimus (TAC) is an essential drug in
the immunosuppressive strategy. Its use constitutes a challenge due to its narrow …

[HTML][HTML] Normothermic regional perfusion can improve both utilization and outcomes in DCD liver, kidney, and pancreas transplantation

Y Bekki, KP Croome, B Myers, K Sasaki… - Transplantation …, 2023 - journals.lww.com
Background. Normothermic regional perfusion (NRP) has gained widespread adoption in
multiple European countries. The aim of this study was to examine the influence of …

[HTML][HTML] Genetic evaluation of living kidney donor candidates: a review and recommendations for best practices

CP Thomas, R Daloul, KL Lentine, R Gohh… - American Journal of …, 2023 - Elsevier
The growing accessibility and falling costs of genetic sequencing techniques has expanded
the utilization of genetic testing in clinical practice. For living kidney donation, genetic …

Characterization of transplant center decisions to allocate kidneys to candidates with lower waiting list priority

KL King, SA Husain, M Yu, JT Adler, J Schold… - JAMA network …, 2023 - jamanetwork.com
Importance Allocation of deceased donor kidneys is meant to follow a ranked match-run list
of eligible candidates, but transplant centers with a 1-to-1 relationship with their local organ …

A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models

O Efe, RB Gassen, L Morena… - The Journal of …, 2024 - Am Soc Clin Investig
Long-term organ transplant survival remains suboptimal, and life-long immunosuppression
predisposes transplant recipients to an increased risk of infection, malignancy, and kidney …

[HTML][HTML] A rational approach to guide cost-effective de novo donor-specific antibody surveillance with tacrolimus immunosuppression

C Wiebe, R Balshaw, IW Gibson, J Ho, J Shaw… - American Journal of …, 2023 - Elsevier
De novo donor-specific antibody (dnDSA) after renal transplantation has been shown to
correlate with antibody-mediated rejection and allograft loss. However, the lack of proven …