Macro (Autophagy) is a catabolic process that relies on the cooperative function of two
organelles: the lysosome and the autophagosome. The recent discovery of a transcriptional …

Fungi are an understudied resource possessing huge potential for develo** products that
can greatly improve human well-being. In the current paper, we highlight some important …

Our understanding of the process of autophagy and its role in health and diseases has
grown remarkably in the last two decades. Early work established autophagy as a general …

Autophagy is a conserved process by which cytoplasmic components are degraded by the
lysosome. It is commonly seen as a cytoplasmic event and, until now, nuclear events were …

CpG island hypermethylation and global genomic hypomethylation are common epigenetic
features of cancer cells. Less attention has been focused on histone modifications in cancer …

Cell identity is determined by specific gene expression patterns that are conveyed by
interactions between transcription factors and DNA in the context of chromatin. In …

Abstract Endogenous retroviruses (ERVs), retrovirus-like elements with long terminal
repeats, are widely dispersed in the euchromatic compartment in mammalian cells …

Aging is the progressive decline or loss of function at the cellular, tissue, and organismal
levels that ultimately leads to death. A number of external and internal factors, including diet …

Inflammation is a defensive reaction for external stimuli to the human body and generally
accompanied by immune responses, which is associated with multiple diseases such as …

Epigenetic marking systems confer stability of gene expression during mammalian
development. Genome-wide epigenetic reprogramming occurs at stages when …