Evidences for adult hippocampal neurogenesis in humans

EP Moreno-Jiménez, J Terreros-Roncal… - Journal of …, 2021 - jneurosci.org
The rodent hippocampus generates new neurons throughout life. This process, named adult
hippocampal neurogenesis (AHN), is a striking form of neural plasticity that occurs in the …

The role of adult hippocampal neurogenesis in brain health and disease

T Toda, SL Parylak, SB Linker, FH Gage - Molecular psychiatry, 2019 - nature.com
Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by a number
of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating …

Adult hippocampal neurogenesis and cognitive flexibility—linking memory and mood

C Anacker, R Hen - Nature Reviews Neuroscience, 2017 - nature.com
Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …

Minocycline alleviates depression-like symptoms by rescuing decrease in neurogenesis in dorsal hippocampus via blocking microglia activation/phagocytosis

B Bassett, S Subramaniyam, Y Fan, S Varney… - Brain, behavior, and …, 2021 - Elsevier
Clinical studies examining the potential of anti-inflammatory agents, specifically of
minocycline, as a treatment for depression has shown promising results. However …

The current state of the neurogenic theory of depression and anxiety

BR Miller, R Hen - Current opinion in neurobiology, 2015 - Elsevier
Highlights•Diverse animal models of depression and anxiety have impaired neurogenesis.•
Neurogenesis is consistently boosted by antidepressants in animal models when animals …

Major depressive disorder

RH Belmaker, G Agam - New England Journal of Medicine, 2008 - Mass Medical Soc
This review of major depressive disorder is a comprehensive account of the genetic,
biochemical, and neurophysiological changes that have been implicated in the disorder. No …

How electroconvulsive therapy works in the treatment of depression: is it the seizure, the electricity, or both?

ZD Deng, PL Robins, W Regenold, P Rohde… - …, 2024 - nature.com
We have known for nearly a century that triggering seizures can treat serious mental illness,
but what we do not know is why. Electroconvulsive Therapy (ECT) works faster and better …