Biological membranes, composed mainly of phospholipids and cholesterol, play a vital role
as cellular barriers. They undergo localized resha** in response to environmental cues …

We have recently developed a novel computational methodology (termed RSF for Real-
Space Fluctuations) to quantify the bending rigidity and tilt modulus of lipid membranes from …

Because lipid bilayers can bend and stretch in ways similar to thin elastic sheets, physical
models of bilayer deformation have utilized mechanical constants such as the moduli for …

The lipid kinase VPS34 orchestrates diverse processes, including autophagy, endocytic
sorting, phagocytosis, anabolic responses and cell division. VPS34 forms various …

Mitochondrial metabolic function is affected by the morphology and protein organization of
the mitochondrial inner membrane. Cardiolipin (CL) is a unique tetra-acyl lipid that is …

Simulations of lipid membranes typically make use of periodic boundary conditions to mimic
macroscopically sized membranes and allow for comparison to experiments performed eg …

Lipid nanodiscs are small synthetic lipid bilayer structures that are stabilized in solution by
special circumscribing (or scaffolding) proteins or polymers. Because they create native-like …

Molecular dynamics is a powerful tool to investigate atomistic and mesoscopic phenomena
in lipid bilayer systems. These studies have progressed with the advent of increased …

The mechanical properties of multilamellar vesicles and their relevance to soft matter
physics and material science are of significant interest. The bending rigidity, κ, and …

Mammalian and Drosophila melanogaster model mitochondrial membrane compositions
are constructed from experimental data. Simplified compositions for inner and outer …