Natural killer cells: from innate to adaptive features
AM Mujal, RB Delconte, JC Sun - Annual review of immunology, 2021 - annualreviews.org
Natural killer (NK) cells are innate lymphocytes that provide critical host defense against
pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells …
pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells …
The broad spectrum of human natural killer cell diversity
Natural killer (NK) cells provide protection against infectious pathogens and cancer. For
decades it has been appreciated that two major NK cell subsets (CD56 bright and CD56 …
decades it has been appreciated that two major NK cell subsets (CD56 bright and CD56 …
Clonal expansion and epigenetic inheritance of long-lasting NK cell memory
Clonal expansion of cells with somatically diversified receptors and their long-term
maintenance as memory cells is a hallmark of adaptive immunity. Here, we studied …
maintenance as memory cells is a hallmark of adaptive immunity. Here, we studied …
Natural killer cell immunotypes related to COVID-19 disease severity
Understanding innate immune responses in coronavirus disease 2019 (COVID-19) is
important to decipher mechanisms of host responses and interpret disease pathogenesis …
important to decipher mechanisms of host responses and interpret disease pathogenesis …
Killer Ig-like receptors (KIRs): their role in NK cell modulation and developments leading to their clinical exploitation
Natural killer (NK) cells contribute to the first line of defense against viruses and to the
control of tumor growth and metastasis spread. The discovery of HLA class I specific …
control of tumor growth and metastasis spread. The discovery of HLA class I specific …
Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells
Natural killer (NK) cells are innate lymphocytes that lack antigen-specific rearranged
receptors, a hallmark of adaptive lymphocytes. In some people infected with human …
receptors, a hallmark of adaptive lymphocytes. In some people infected with human …
Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference map**
The functional diversity of natural killer (NK) cell repertoires stems from differentiation,
homeostatic, receptor–ligand interactions and adaptive-like responses to viral infections. In …
homeostatic, receptor–ligand interactions and adaptive-like responses to viral infections. In …
Natural killer cell memory in infection, inflammation and cancer
A Cerwenka, LL Lanier - Nature Reviews Immunology, 2016 - nature.com
Immunological memory can be defined as a quantitatively and qualitatively enhanced
immune response upon rechallenge. For natural killer (NK) cells, two main types of memory …
immune response upon rechallenge. For natural killer (NK) cells, two main types of memory …
Human NK cells, their receptors and function
NK cells are cytotoxic components of innate lymphoid cells (ILC) that provide a first line of
defense against viral infections and contribute to control tumor growth and metastasis. Their …
defense against viral infections and contribute to control tumor growth and metastasis. Their …
Aging of the immune system: focus on inflammation and vaccination
M Pinti, V Appay, J Campisi, D Frasca… - European journal of …, 2016 - Wiley Online Library
Major advances in preventing, delaying, or curing individual pathologies are responsible for
an increasingly long life span in the developed parts of our planet, and indeed reaching …
an increasingly long life span in the developed parts of our planet, and indeed reaching …