Root mean-square deviation (RMSD) after roto-translational least-squares fitting is a
measure of global structural similarity of macromolecules used commonly. On the other …

Biomolecular X-ray structures typically provide a static, time-and ensemble-averaged view of
molecular ensembles in crystals. In the absence of rigid-body motions and lattice defects, B …

Protein thermal stability is an important factor considered in medical and industrial
applications. Many structural characteristics related to protein thermal stability have been …

Enterovirus 71 (EV71) and coxsackievirus (CVA) are the most common causative factors for
hand, foot, and mouth disease (HFMD) and neurological disorders in children. Lack of a …

Enterovirus (EV) 71 infection is known to cause hand-foot-and-mouth disease (HFMD) and
in severe cases, induces neurological disorders culminating in fatality. An outbreak of EV71 …

Although several factors participating in enterovirus 71 (EV71) entry and replication had
been reported, the precise mechanisms associated with these events are far from clear. In …

We investigate the relationship between the flexibility, expressed with B‐factor, and the
relative solvent accessibility (RSA) in the context of local, with respect to the sequence …

Thermostability remains one of the most desirable traits in many lipases. Numerous studies
have revealed promising strategies to improve thermostability and random mutagenesis …

The knowledge of conserved sequences in proteins is valuable in identifying functionally or
structurally important residues. Generating the conservation profile of a sequence requires …

Enterovirus 71 (EV71) and coxsackieviruses (CV) are the major causative agents of hand,
foot and mouth disease (HFMD). There is not currently a vaccine available against HFMD …